Compile Data Set for Download or QSAR
Report error Found 141 Enz. Inhib. hit(s) with all data for entry = 8497
TargetBaculoviral IAP repeat-containing protein 2 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 254000BDBM254000(US9481673, (S)-10)
Affinity DataIC50: 1nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 254001BDBM254001(US9481673, (S)-11)
Affinity DataIC50: 1nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253998BDBM253998(US9481673, (S)-8)
Affinity DataIC50: 1nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253999BDBM253999(US9481673, (S)-9)
Affinity DataIC50: 1nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253996BDBM253996(US9481673, (S)-6)
Affinity DataIC50: 1nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253997BDBM253997(US9481673, (S)-7)
Affinity DataIC50: 1nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253994BDBM253994(US9481673, (S)-4)
Affinity DataIC50: 1nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253992BDBM253992(US9481673, (S)-2)
Affinity DataIC50: 1nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253993BDBM253993(US9481673, (S)-3)
Affinity DataIC50: 1nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253991BDBM253991(US9481673, (S)-1)
Affinity DataIC50: 1nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 254004BDBM254004(US9481673, (S)-14)
Affinity DataIC50: 1nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 254003BDBM254003(US9481673, (S)-13)
Affinity DataIC50: 1nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253995BDBM253995(US9481673, (S)-5)
Affinity DataIC50: 2nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 254006BDBM254006(US9481673, (S)-16)
Affinity DataIC50: 2nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 254005BDBM254005(US9481673, (S)-15)
Affinity DataIC50: 2nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 254002BDBM254002(US9481673, (S)-12)
Affinity DataIC50: 2nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 254001BDBM254001(US9481673, (S)-11)
Affinity DataIC50: 13nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253996BDBM253996(US9481673, (S)-6)
Affinity DataIC50: 108nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253997BDBM253997(US9481673, (S)-7)
Affinity DataIC50: 124nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253998BDBM253998(US9481673, (S)-8)
Affinity DataIC50: 147nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 254005BDBM254005(US9481673, (S)-15)
Affinity DataIC50: 175nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253991BDBM253991(US9481673, (S)-1)
Affinity DataIC50: 207nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 254003BDBM254003(US9481673, (S)-13)
Affinity DataIC50: 219nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253993BDBM253993(US9481673, (S)-3)
Affinity DataIC50: 252nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 254000BDBM254000(US9481673, (S)-10)
Affinity DataIC50: 260nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253999BDBM253999(US9481673, (S)-9)
Affinity DataIC50: 267nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 2C8(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253985BDBM253985(US9481673, 27)
Affinity DataIC50: 300nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 2C8(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253988BDBM253988(US9481673, 82)
Affinity DataIC50: 300nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253994BDBM253994(US9481673, (S)-4)
Affinity DataIC50: 303nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 254006BDBM254006(US9481673, (S)-16)
Affinity DataIC50: 304nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 254002BDBM254002(US9481673, (S)-12)
Affinity DataIC50: 333nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253988BDBM253988(US9481673, 82)
Affinity DataIC50: 400nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253986BDBM253986(US9481673, 64)
Affinity DataIC50: 400nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253985BDBM253985(US9481673, 27)
Affinity DataIC50: 400nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 2C8(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253986BDBM253986(US9481673, 64)
Affinity DataIC50: 500nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253995BDBM253995(US9481673, (S)-5)
Affinity DataIC50: 677nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253989BDBM253989(US9481673, 94)
Affinity DataIC50: 700nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253987BDBM253987(US9481673, 81)
Affinity DataIC50: 900nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 2C8(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253992BDBM253992(US9481673, (S)-2)
Affinity DataIC50: 900nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 2C8(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253987BDBM253987(US9481673, 81)
Affinity DataIC50: 1.20E+3nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 254004BDBM254004(US9481673, (S)-14)
Affinity DataIC50: 1.27E+3nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 2C8(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253995BDBM253995(US9481673, (S)-5)
Affinity DataIC50: 1.30E+3nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 2C8(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253998BDBM253998(US9481673, (S)-8)
Affinity DataIC50: 1.60E+3nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 2C8(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253990BDBM253990(US9481673, 185)
Affinity DataIC50: 1.70E+3nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 2C19(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253992BDBM253992(US9481673, (S)-2)
Affinity DataIC50: 1.90E+3nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253986BDBM253986(US9481673, 64)
Affinity DataIC50: 2.10E+3nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253988BDBM253988(US9481673, 82)
Affinity DataIC50: 2.20E+3nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 2C8(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 254005BDBM254005(US9481673, (S)-15)
Affinity DataIC50: 2.20E+3nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253988BDBM253988(US9481673, 82)
Affinity DataIC50: 2.30E+3nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 253990BDBM253990(US9481673, 185)
Affinity DataIC50: 2.70E+3nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent

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