Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 8490
TargetCytochrome P450 2D6(Human)
Leo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 50416875BDBM50416875(CINACALCET | AMG-073 | AMG073 HCL | CINACALCET HYD...)
Affinity DataIC50: 50nMpH: 7.4 T: 2°CAssay Description:Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Leo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 253032BDBM253032(US9487494, 53 (Compound 1056))
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Leo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 253030BDBM253030(US9487494, 127 (Compound 1136))
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Leo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 253031BDBM253031(US9487494, 106 (Compound 1115))
Affinity DataIC50: 1.30E+4nMpH: 7.4 T: 2°CAssay Description:Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Leo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 253028BDBM253028(US9487494, 137 (Compound 1146))
Affinity DataIC50: 1.60E+4nMpH: 7.4 T: 2°CAssay Description:Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Leo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 253029BDBM253029(US9487494, 133 (Compound 1142))
Affinity DataIC50: 2.50E+4nMpH: 7.4 T: 2°CAssay Description:Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Leo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 253025BDBM253025(US9487494, 171 (Compound 1186))
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Leo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 253026BDBM253026(US9487494, 175 (Compound 1190))
Affinity DataIC50: 7.90E+4nMpH: 7.4 T: 2°CAssay Description:Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Leo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 253027BDBM253027(US9487494, 299 (Compound 1338))
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Incubations were conducted in 96 well microtiter plates based on a method described by BD Biosciences. To the first well in each row, a NADPH regener...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent