Compile Data Set for Download or QSAR
Report error Found 75 Enz. Inhib. hit(s) with all data for entry = 195
LigandChemical structure of BindingDB Monomer ID 247218BDBM247218(US9434733, methyl 5-[[3-methyl-4-(4-oxo-7-tetrahyd...)
Affinity DataIC50: 8nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247206BDBM247206(US9434733, 2-[[3-[(4-fluorophenyl)methoxy]azetidin...)
Affinity DataIC50: 10nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247177BDBM247177(US9434733, 2-[4-methyl-1-[[4-(trifluoromethyl)phen...)
Affinity DataIC50: 12nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247192BDBM247192(US9434733, 2-[1-[[4-(diethylamino)phenyl]methyl]-4...)
Affinity DataIC50: 13nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247225BDBM247225(US9434733, 2-[1-[(5-chloro-2-thienyl)methyl]-4-met...)
Affinity DataIC50: 13nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247183BDBM247183(US9434733, 2-[4-methyl-1-[[4-(trifluoromethoxy)phe...)
Affinity DataIC50: 19nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247195BDBM247195(US9434733, 2-[1-[(2-chloro-4-fluoro-phenyl)methyl]...)
Affinity DataIC50: 21nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247224BDBM247224(US9434733, 2-[4-methyl-1-[(5-methyl-2-thienyl)meth...)
Affinity DataIC50: 22nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247222BDBM247222(US9434733, 2-[(1R)-1-[3-(4-methoxyphenyl)azetidin-...)
Affinity DataIC50: 22nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247215BDBM247215(US9434733, 2-[1-[(3,4-difluorophenyl)methyl]-4-met...)
Affinity DataIC50: 23nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247186BDBM247186(US9434733, 2-[4-methyl-1-(quinoxalin-6-ylmethyl)py...)
Affinity DataIC50: 24nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247213BDBM247213(US9434733, 2-[1-[(5-fluoro-3-pyridyl)methyl]-4-met...)
Affinity DataIC50: 25nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247193BDBM247193(US9434733, 2-[1-(2-furylmethyl)-4-methyl-pyrrolidi...)
Affinity DataIC50: 25nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247196BDBM247196(US9434733, 2-[1-[(4-dimethylaminophenyl)methyl]-4-...)
Affinity DataIC50: 27nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247208BDBM247208(US9434733, 2-[4-methyl-1-[(5-methyl-2-furyl)methyl...)
Affinity DataIC50: 28nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247216BDBM247216(US9434733, 2-[1-[(4-chlorophenyl)methyl]-4-methyl-...)
Affinity DataIC50: 32nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247217BDBM247217(US9434733, 2-[1-[[6-(dimethylamino)-3-pyridyl]meth...)
Affinity DataIC50: 36nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247203BDBM247203(US9434733, 2-[4-methyl-1-(3-pyridylmethyl)pyrrolid...)
Affinity DataIC50: 37nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247185BDBM247185(US9434733, 2-[1-[(2-chloro-4-methoxy-phenyl)methyl...)
Affinity DataIC50: 41nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247207BDBM247207(US9434733, 2-[1-[3-(4-methoxyphenyl)azetidin-1-yl]...)
Affinity DataIC50: 47nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247221BDBM247221(US9434733, 2-[(3R,4R)-1-[(2,4-difluorophenyl)methy...)
Affinity DataIC50: 47nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247197BDBM247197(US9434733, 2-[4-methyl-1-(p-tolylmethyl)pyrrolidin...)
Affinity DataIC50: 47nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247181BDBM247181(US9434733, 2-[1-[(2,4-difluorophenyl)methyl]-4-met...)
Affinity DataIC50: 48nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247188BDBM247188(US9434733, 2-[1-[(4-methoxyphenyl)methyl]-4-methyl...)
Affinity DataIC50: 49nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247236BDBM247236(US9434733, 2-[1-benzyl-4-(trifluoromethyl)pyrrolid...)
Affinity DataIC50: 50nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247189BDBM247189(US9434733, 2-[4-methyl-1-(4-pyridylmethyl)pyrrolid...)
Affinity DataIC50: 52nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247227BDBM247227(US9434733, 2-(1-benzyl-4-methoxy-pyrrolidin-3-yl)-...)
Affinity DataIC50: 54nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247223BDBM247223(US9434733, 2-[1-[3-(4-fluorophenoxy)azetidin-1-yl]...)
Affinity DataIC50: 57nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247226BDBM247226(US9434733, 2-[4-methyl-1-[(4-pyrrolidin-1-ylphenyl...)
Affinity DataIC50: 61nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247204BDBM247204(US9434733, 2-[1-[(2,6-difluorophenyl)methyl]-4-met...)
Affinity DataIC50: 62nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247209BDBM247209(US9434733, 2-[1-[(5-chloro-2-furyl)methyl]-4-methy...)
Affinity DataIC50: 63nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247176BDBM247176(US9434733, 2-[1-[(6-methoxy-3-pyridyl)methyl]-4-me...)
Affinity DataIC50: 67nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247244BDBM247244(US9434733, 2-[1-[3-[(4-methoxyphenyl)methyl]azetid...)
Affinity DataIC50: 68nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247190BDBM247190(US9434733, 2-[[3-(4-fluorophenoxy)azetidin-1-yl]me...)
Affinity DataIC50: 80nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247233BDBM247233(US9434733, 2-[[3-[(4-methoxyphenoxy)methyl]azetidi...)
Affinity DataIC50: 82nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247233BDBM247233(US9434733, 2-[[3-[(4-methoxyphenoxy)methyl]azetidi...)
Affinity DataIC50: 82nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247239BDBM247239(US9434733, 2-[4-methoxy-1-[(4-methoxyphenyl)methyl...)
Affinity DataIC50: 83nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247175BDBM247175(US9434733, 7-(4-fluorophenyl)-2-[4-methyl-1-[[6-(t...)
Affinity DataIC50: 86nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247238BDBM247238(US9434733, 2-[1-[3-(4-dimethylaminophenyl)azetidin...)
Affinity DataIC50: 86nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247202BDBM247202(US9434733, 2-[[3-(4-dimethylaminophenyl)azetidin-1...)
Affinity DataIC50: 86nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247230BDBM247230(US9434733, 2-[4-methoxy-1-(p-tolylmethyl)pyrrolidi...)
Affinity DataIC50: 90nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247212BDBM247212(US9434733, 2-[[3-(4-methylphenoxy)azetidin-1-yl]me...)
Affinity DataIC50: 91nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247229BDBM247229(US9434733, 2-[1-[(4-fluorophenyl)methyl]-4-methoxy...)
Affinity DataIC50: 94nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247235BDBM247235(US9434733, 2-[1-[3-(4-pyrrolidin-1-ylphenyl)azetid...)
Affinity DataIC50: 110nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247235BDBM247235(US9434733, 2-[1-[3-(4-pyrrolidin-1-ylphenyl)azetid...)
Affinity DataIC50: 110nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247232BDBM247232(US9434733, 2-[1-[3-(4-methylphenoxy)azetidin-1-yl]...)
Affinity DataIC50: 110nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247245BDBM247245(US9434733, 7-tetrahydropyran-4-yl-2-[1-[3-[4-(trif...)
Affinity DataIC50: 110nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247237BDBM247237(US9434733, 2-[[3-(5-pyrrolidin-1-ylpyrimidin-2-yl)...)
Affinity DataIC50: 120nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247228BDBM247228(US9434733, 2-[1-[3-(4-hydroxyphenyl)azetidin-1-yl]...)
Affinity DataIC50: 120nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 247210BDBM247210(US9434733, 2-[1-[3-(4-fluorophenyl)azetidin-1-yl]e...)
Affinity DataIC50: 128nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent

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