Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 169
TargetHistamine receptor H3(Rhesus macaque)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 200837BDBM200837(2-[2-((2s,3's)-2-methyl-[1,3']bipyrrolidin...)
Affinity DataKi:  4.21nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetHistamine receptor H3(Rhesus macaque)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 200827BDBM200827(2-[2-methyl-6-((2s,3's)-2-methyl-[1,3']bip...)
Affinity DataKi:  7.10nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetHistamine receptor H3(Rhesus macaque)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 200831BDBM200831(2-[2-methyl-6-((2s,3's)-2-methyl-[1,3']bip...)
Affinity DataKi:  7.57nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetHistamine receptor H3(Rhesus macaque)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 200828BDBM200828(2-[2-methyl-6-((2s,3'r)-2-methyl-[1,3']bip...)
Affinity DataKi:  17.5nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetHistamine receptor H3(Rhesus macaque)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 200833BDBM200833(2-[5-((2s,3's)-2-methyl-[1,3']bipyrrolidin...)
Affinity DataKi:  22.3nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetHistamine receptor H3(Rhesus macaque)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 200830BDBM200830(2-[5-((2s,3's)-2-methyl-[1,3']bipyrrolidin...)
Affinity DataKi:  26.3nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetHistamine receptor H3(Rhesus macaque)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 200815BDBM200815(1 2-[2-Methyl-6-((2S,3′R)-2-methyl-[1,3̸...)
Affinity DataKi:  37.6nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetHistamine receptor H3(Rhesus macaque)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 200829BDBM200829(2-[2-methyl-6-((2s,3'r)-2-methyl-[1,3']bip...)
Affinity DataKi:  38.9nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetHistamine receptor H3(Rhesus macaque)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 200832BDBM200832(2-[2-((2s,3's)-2-methyl-[1,3']bipyrrolidin...)
Affinity DataKi:  48.5nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetHistamine receptor H3(Rhesus macaque)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 200823BDBM200823(2-[2-methyl-6-((2s,3'r)-2-methyl-[1,3']bip...)
Affinity DataKi:  56.5nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetHistamine receptor H3(Rhesus macaque)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 200821BDBM200821(2-[2-methyl-6-((2s,3'r)-2-methyl-[1,3']bip...)
Affinity DataKi:  95.1nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetHistamine receptor H3(Rhesus macaque)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 200836BDBM200836(2-[2-methyl-6-((2s,3's)-2-methyl-[1,3']bip...)
Affinity DataKi:  95.5nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetHistamine receptor H3(Rhesus macaque)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 200834BDBM200834(2-[5-((2s,3's)-2-methyl-[1,3']bipyrrolidin...)
Affinity DataKi:  105nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetHistamine receptor H3(Rhesus macaque)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 200822BDBM200822(8-hydroxy-2-[2-methyl-6-((2s,3'r)-2-methyl-[1,...)
Affinity DataKi:  267nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent