Compile Data Set for Download or QSAR
Report error Found 95 Enz. Inhib. hit(s) with all data for entry = 499
TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274412BDBM274412(US95556117, Example 76,4-Chloro-7-methoxy-1H-indol...)
Affinity DataIC50: 2.90nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274361BDBM274361(US95556117, Example 25,4-Chloro-7-methyl-1H-indole...)
Affinity DataIC50: 2.90nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274348BDBM274348(US95556117, Example 12,4-Chloro-1H-indole-5-carbox...)
Affinity DataIC50: 3.20nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274419BDBM274419(US95556117, Example 83,4-Chloro-7-propyl-1H-indole...)
Affinity DataIC50: 3.30nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274418BDBM274418(US95556117, Example 82,4-Chloro-7-propyl-1H-indole...)
Affinity DataIC50: 3.80nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274399BDBM274399(US95556117, Example 63,4,7-Dimethyl-1H-indole-5-ca...)
Affinity DataIC50: 4nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274397BDBM274397(US95556117, Example 61,4-Chloro-7-methyl-1H-indole...)
Affinity DataIC50: 4nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274398BDBM274398(US95556117, Example 62,4-Chloro-7-methyl-1H-indole...)
Affinity DataIC50: 4.10nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274347BDBM274347(US95556117, Example 11,4-Chloro-1H-indole-5-carbox...)
Affinity DataIC50: 4.10nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274408BDBM274408(US95556117, Example 72,4-Chloro-7-ethyl-1H-indole-...)
Affinity DataIC50: 4.10nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274409BDBM274409(US95556117, Example 73,4-Chloro-7-ethyl-1H-indole-...)
Affinity DataIC50: 4.20nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274389BDBM274389(US95556117, Example 53,4-Chloro-7-(3-methoxy-propy...)
Affinity DataIC50: 4.40nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274350BDBM274350(US95556117, Example 14,4-Chloro-1H-indole-5-carbox...)
Affinity DataIC50: 4.5nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274403BDBM274403(US95556117, Example 67,rac-4-Chloro-7-(1-hydroxy-e...)
Affinity DataIC50: 4.70nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274360BDBM274360(US95556117, Example 24,4-Chloro-7-methyl-1H-indole...)
Affinity DataIC50: 4.70nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274417BDBM274417(US95556117, Example 81,4-Chloro-7-ethoxy-1H-indole...)
Affinity DataIC50: 5.40nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274395BDBM274395(US95556117, Example 59,4-Chloro-7-methoxy-1H-indol...)
Affinity DataIC50: 5.40nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274388BDBM274388(US95556117, Example 52,4-Chloro-7-isobutyl-1H-indo...)
Affinity DataIC50: 5.90nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274415BDBM274415(US95556117, Example 79,4-Chloro-7-ethoxy-1H-indole...)
Affinity DataIC50: 6.10nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274356BDBM274356(US95556117, Example 20,4-Chloro-7-methyl-1H-indole...)
Affinity DataIC50: 6.10nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274396BDBM274396(US95556117, Example 60,4-Chloro-1H-indole-5-carbox...)
Affinity DataIC50: 6.30nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274394BDBM274394(US95556117, Example 58,4-Chloro-1H-indole-5-carbox...)
Affinity DataIC50: 6.40nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274391BDBM274391(US95556117, Example 55,4-Chloro-7-(3-methoxy-propy...)
Affinity DataIC50: 6.70nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274422BDBM274422(US95556117, Example 86,4-Chloro-7-(2-hydroxy-ethox...)
Affinity DataIC50: 6.70nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274404BDBM274404(US95556117, Example 68,4-Chloro-7-(1-hydroxy-1-met...)
Affinity DataIC50: 7.20nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274423BDBM274423(US95556117, Example 87,4-Chloro-7-(2-hydroxy-ethox...)
Affinity DataIC50: 7.30nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274425BDBM274425(US95556117, Example 89,4-Chloro-7-(1-hydroxy-1-met...)
Affinity DataIC50: 8.30nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274392BDBM274392(US95556117, Example 56,4-Chloro-1H-indole-5-carbox...)
Affinity DataIC50: 9nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274431BDBM274431(US95556117, Example 95,4-Chloro-7-(1-methoxy-1-met...)
Affinity DataIC50: 9.30nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274430BDBM274430(US95556117, Example 94,4-Chloro-7-(2-ethoxy-ethyl)...)
Affinity DataIC50: 9.40nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274411BDBM274411(US95556117, Example 75,7-Chloro-4-methyl-1H-indole...)
Affinity DataIC50: 9.5nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274406BDBM274406(US95556117, Example 70,7-Methyl-4-trifluoromethyl-...)
Affinity DataIC50: 10nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274405BDBM274405(US95556117, Example 69,7-Methyl-4-trifluoromethyl-...)
Affinity DataIC50: 10nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274368BDBM274368(US95556117, Example 32,7-Amino-4-chloro-1H-indole-...)
Affinity DataIC50: 11nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274362BDBM274362(US95556117, Example 26,4-Chloro-3-fluoro-1H-indole...)
Affinity DataIC50: 11.4nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274339BDBM274339(US95556117, Example 3,4-Chloro-1H-indole-5-carboxy...)
Affinity DataIC50: 12nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274407BDBM274407(US95556117, Example 71,4,7-Dimethyl-1H-indole-5-ca...)
Affinity DataIC50: 12nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274337BDBM274337(US95556117, Example 1,4-Chloro-1H-indole-5-carboxy...)
Affinity DataIC50: 13nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274390BDBM274390(US95556117, Example 54,4-Chloro-7-isobutyl-1H-indo...)
Affinity DataIC50: 13nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274353BDBM274353(US95556117, Example 17,4-Chloro-1H-indole-5-carbox...)
Affinity DataIC50: 14nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274378BDBM274378(US95556117, Example 42,4-Chloro-1H-indole-5-carbox...)
Affinity DataIC50: 14nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274349BDBM274349(US95556117, Example 13,4-Chloro-1H-indole-5-carbox...)
Affinity DataIC50: 17nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274410BDBM274410(US95556117, Example 74,7-Chloro-4-methyl-1H-indole...)
Affinity DataIC50: 17nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274355BDBM274355(US95556117, Example 19,4-Chloro-1H-indole-5-carbox...)
Affinity DataIC50: 18nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274365BDBM274365(US95556117, Example 29,4-Chloro-7-nitro-1H-indole-...)
Affinity DataIC50: 20nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274383BDBM274383(US95556117, Example 47,4-Chloro-1H-indole-5-carbox...)
Affinity DataIC50: 21nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274414BDBM274414(US95556117, Example 78,7-Methoxy-4-methyl-1H-indol...)
Affinity DataIC50: 21nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274413BDBM274413(US95556117, Example 77,7-Methoxy-4-methyl-1H-indol...)
Affinity DataIC50: 21nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274387BDBM274387(US95556117, Example 51,(1-{[(4-Chloro-1H-indole-5-...)
Affinity DataIC50: 24nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 274402BDBM274402(US95556117, Example 66,7-Acetyl-4-chloro-1H-indole...)
Affinity DataIC50: 24nMAssay Description:The amplified sequence was subsequently ligated into a pcDNA3.1 (+) NotI, NheI digested plasmid. Human embryonic kidney (HEK) cells (ATCC CRL-1573, M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

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