Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 982
TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 50189180BDBM50189180(CHEMBL3827257 | US9597326, Compound 18)
Affinity DataEC50:  5nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 50189282BDBM50189282(CHEMBL3828331 | US9597326, Compound 15)
Affinity DataEC50:  65nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 50189287BDBM50189287(CHEMBL3827413 | US9597326, Compound 11)
Affinity DataEC50:  90nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 50189281BDBM50189281(CHEMBL3827669 | US9597326, Compound 16)
Affinity DataEC50:  137nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 50189289BDBM50189289(CHEMBL3828519 | US9597326, Compound 10)
Affinity DataEC50:  153nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 50189288BDBM50189288(CHEMBL3828701 | US9597326, Compound 12)
Affinity DataEC50:  201nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 301806BDBM301806(US9597326, Compound 22)
Affinity DataEC50:  204nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 50189286BDBM50189286(CHEMBL3827244 | US9597326, Compound 1)
Affinity DataEC50:  226nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 50189285BDBM50189285(CHEMBL3828296 | US9597326, Compound 5)
Affinity DataEC50:  308nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 301783BDBM301783(US9597326, Compound 2)
Affinity DataEC50:  315nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 301804BDBM301804(US9597326, Compound 20)
Affinity DataEC50:  360nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 301789BDBM301789(US9597326, Compound 8)
Affinity DataEC50:  375nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 50189181BDBM50189181(CHEMBL3828229 | US9597326, Compound 21)
Affinity DataEC50:  384nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 50189290BDBM50189290(CHEMBL3828149 | US9597326, Compound 9)
Affinity DataEC50:  390nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 301785BDBM301785(US9597326, Compound 4)
Affinity DataEC50:  559nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 301808BDBM301808(US9597326, Compound 24)
Affinity DataEC50:  791nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 50189291BDBM50189291(CHEMBL3827959 | US9597326, Compound 14)
Affinity DataEC50:  885nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 301810BDBM301810(US9597326, Compound 26)
Affinity DataEC50:  975nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 301788BDBM301788(US9597326, Compound 7)
Affinity DataEC50:  1.01E+3nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 301798BDBM301798(US9597326, Compound 13)
Affinity DataEC50:  1.05E+3nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 301807BDBM301807(US9597326, Compound 23)
Affinity DataEC50:  1.16E+3nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 50189283BDBM50189283(CHEMBL3828542 | US9597326, Compound 6)
Affinity DataEC50:  1.64E+3nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 50189284BDBM50189284(CHEMBL3828386 | US9597326, Compound 27)
Affinity DataEC50:  2.59E+3nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 301784BDBM301784(US9597326, Compound 3)
Affinity DataEC50:  3.17E+3nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 301809BDBM301809(US9597326, Compound 25)
Affinity DataEC50:  4.26E+3nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 301803BDBM301803(US9597326, Compound 19)
Affinity DataEC50:  2.38E+4nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent