Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 990
TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301927BDBM301927(US9598396, Compound 4)
Affinity DataIC50: 0.933nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301928BDBM301928(US9598396, Compound 5)
Affinity DataIC50: 0.977nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301932BDBM301932(US9598396, Compound 7)
Affinity DataIC50: 4.17nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301932BDBM301932(US9598396, Compound 7)
Affinity DataIC50: 9.55nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301923BDBM301923(US9598396, Compound 1)
Affinity DataIC50: 14.1nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301929BDBM301929(US9598396, Compound 5a)
Affinity DataIC50: 15.8nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301927BDBM301927(US9598396, Compound 4)
Affinity DataIC50: 17.4nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301931BDBM301931(US9598396, Compound 6)
Affinity DataIC50: 19.1nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301928BDBM301928(US9598396, Compound 5)
Affinity DataIC50: 19.5nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301940BDBM301940(US9598396, Compound 15)
Affinity DataIC50: 33.1nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301926BDBM301926(US9598396, Compound 3)
Affinity DataIC50: 33.1nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301930BDBM301930(US9598396, Compound 5b)
Affinity DataIC50: 33.9nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301936BDBM301936(US9598396, Compound 11)
Affinity DataIC50: 35.5nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301930BDBM301930(US9598396, Compound 5b)
Affinity DataIC50: 36.3nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301923BDBM301923(US9598396, Compound 1)
Affinity DataIC50: 36.3nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301924BDBM301924(US9598396, Compound 2)
Affinity DataIC50: 37.2nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301942BDBM301942(US9598396, Compound 16)
Affinity DataIC50: 38nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301929BDBM301929(US9598396, Compound 5a)
Affinity DataIC50: 39.8nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301940BDBM301940(US9598396, Compound 15)
Affinity DataIC50: 40.7nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301938BDBM301938(US9598396, Compound 13 | BDBM301939)
Affinity DataIC50: 41.7nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301937BDBM301937(US9598396, Compound 12)
Affinity DataIC50: 42.7nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301938BDBM301938(US9598396, Compound 13 | BDBM301939)
Affinity DataIC50: 42.7nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301945BDBM301945(US9598396, Compound 17)
Affinity DataIC50: 44.7nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301937BDBM301937(US9598396, Compound 12)
Affinity DataIC50: 45.7nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301924BDBM301924(US9598396, Compound 2)
Affinity DataIC50: 46.8nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301933BDBM301933(US9598396, Compound 8)
Affinity DataIC50: 52.5nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301945BDBM301945(US9598396, Compound 17)
Affinity DataIC50: 52.5nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301931BDBM301931(US9598396, Compound 6)
Affinity DataIC50: 53.7nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301926BDBM301926(US9598396, Compound 3)
Affinity DataIC50: 55nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301935BDBM301935(US9598396, Compound 10)
Affinity DataIC50: 58.9nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301938BDBM301938(US9598396, Compound 13 | BDBM301939)
Affinity DataIC50: 63.1nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301934BDBM301934(US9598396, Compound 9)
Affinity DataIC50: 63.1nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301946BDBM301946(US9598396, Compound 19)
Affinity DataIC50: 64.6nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301933BDBM301933(US9598396, Compound 8)
Affinity DataIC50: 83.2nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301936BDBM301936(US9598396, Compound 11)
Affinity DataIC50: 87.1nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301938BDBM301938(US9598396, Compound 13 | BDBM301939)
Affinity DataIC50: 97.7nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301935BDBM301935(US9598396, Compound 10)
Affinity DataIC50: 219nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301934BDBM301934(US9598396, Compound 9)
Affinity DataIC50: 447nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 301942BDBM301942(US9598396, Compound 16)
Affinity DataIC50: 794nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent