Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 1178
TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309528(US9603834, 27 | N-{5-chloro-2-[(2-thienylsulfonyl)...)
Affinity DataIC50: 20nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309524(US9603834, 23 | N-{4,5-dichloro-2-[(2-thienylsulfo...)
Affinity DataIC50: 96nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309527(US9603834, 26 | N-{4-chloro-2-[(2-thienylsulfonyl)...)
Affinity DataIC50: 145nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309515(US9603834, 14 | N-(5-chloro-2-{[(2,6-difluoropheny...)
Affinity DataIC50: 153nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309522(US9603834, 21 | N-{2-[(1-benzofuran-2-ylsulfonyl)a...)
Affinity DataIC50: 183nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309520(US9603834, 19 | N-{2-[(1-benzofuran-2-ylsulfonyl)a...)
Affinity DataIC50: 185nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309510(N-(4,5-dichloro-2-{[(3-chloro-2-fluorophenyl)sulfo...)
Affinity DataIC50: 217nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309504(US9603834, 3 | methyl 3-[({2-[(1-benzofuran-2-ylsu...)
Affinity DataIC50: 246nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309502(US9603834, 1 | 5-chloro-N-{4,5-dichloro-2-[(2-thie...)
Affinity DataIC50: 263nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309503(US9603834, 2 | 6-chloro-N-{4,5-dichloro-2-[(2-thie...)
Affinity DataIC50: 281nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309523(US9603834, 22 | N-{2-[(1-benzofuran-2-ylsulfonyl)a...)
Affinity DataIC50: 294nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309518(US9603834, 17 | N-[4,5-dichloro-2-({[3-(trifluorom...)
Affinity DataIC50: 306nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309526(US9603834, 25 | N-{4,5-dichloro-2-[(2-thienylsulfo...)
Affinity DataIC50: 311nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309516(US9603834, 15 | N-(5-chloro-2-{[(5-methyl-2-thieny...)
Affinity DataIC50: 339nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309517(US9603834, 16 | N-[3-({[4-chloro-3-(trifluoromethy...)
Affinity DataIC50: 349nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309512(US9603834, 11 | N-(4,5-dichloro-2-{[(4-chloro-2-fl...)
Affinity DataIC50: 361nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309510(N-(4,5-dichloro-2-{[(3-chloro-2-fluorophenyl)sulfo...)
Affinity DataIC50: 391nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309508(US9603834, 7 | N-(4,5-dichloro-2-{[(3,4-dichloroph...)
Affinity DataIC50: 394nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309507(US9603834, 6 | N-(4,5-dichloro-2-{[(2-fluorophenyl...)
Affinity DataIC50: 402nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309521(US9603834, 20 | N-{2-[(1-benzofuran-2-ylsulfonyl)a...)
Affinity DataIC50: 423nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309519(US9603834, 18 | N-[4,5-dichloro-2-({[4-fluoro-3-(t...)
Affinity DataIC50: 432nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309513(US9603834, 12 | N-(4,5-dichloro-2-{[(4-fluoropheny...)
Affinity DataIC50: 441nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309506(US9603834, 5 | N-(4,5-dichloro-2-{[(2,4-difluoroph...)
Affinity DataIC50: 451nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309505(US9603834, 4 | N-(2-{[(4-bromo-3-methylphenyl)sulf...)
Affinity DataIC50: 471nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309514(US9603834, 13 | N-(5-chloro-2-{[(2,6-dichloropheny...)
Affinity DataIC50: 478nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309509(US9603834, 8 | N-(4,5-dichloro-2-{[(3,5-dichloro-2...)
Affinity DataIC50: 482nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309525(US9603834, 24 | N-{4,5-dichloro-2-[(2-thienylsulfo...)
Affinity DataIC50: 494nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent