Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 159 Enz. Inhib. hit(s) with all data for entry = 1217
TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312567(1-[4-(6-Methoxy-7,8-dimethyl-3-phenylimidazo[1,2-b...)
Affinity DataIC50:  2.40nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312579(US9604989, Example 65)
Affinity DataIC50:  2.60nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312522(2-[4-(1-Aminocyclobutyl)phenyl]-8-methoxy-3-phenyl...)
Affinity DataIC50:  2.60nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312579(US9604989, Example 65)
Affinity DataIC50:  3.10nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312575(US9604989, Example 61)
Affinity DataIC50:  3.70nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312548(US9604989, Example 34)
Affinity DataIC50:  3.90nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312521(1-[4-(6,8-Dimethyloxy-3-phenylimidazo[1,2-b]pyrida...)
Affinity DataIC50:  3.90nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312522(2-[4-(1-Aminocyclobutyl)phenyl]-8-methoxy-3-phenyl...)
Affinity DataIC50:  4.10nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312575(US9604989, Example 61)
Affinity DataIC50:  4.10nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312518(1-[4-(6-Methyloxy-3-phenylimidazo[1,2-b]pyridazin-...)
Affinity DataIC50:  4.20nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312587(1-{4-[6-Methoxy-3-phenyl-8-(1H-pyrazol-3-yl)imidaz...)
Affinity DataIC50:  4.30nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312527(US9604989, Example 15)
Affinity DataIC50:  4.40nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312578(US9604989, Example 64)
Affinity DataIC50:  4.80nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312541(US9604989, Example 28)
Affinity DataIC50:  5nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312517(2-[4-(1-Aminocyclobutyl)phenyl]-3-phenylimidazo[1,...)
Affinity DataIC50:  5.20nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312541(US9604989, Example 28)
Affinity DataIC50:  5.40nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312539(US9604989, Example 26)
Affinity DataIC50:  6.30nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312570(Methyl 2-[4-(1-aminocyclobutyl)phenyl]-3-phenyl-8-...)
Affinity DataIC50:  6.60nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312519(1-[4-(6-Bromo-8-methyloxy-3-phenylimidazo[1,2-b]py...)
Affinity DataIC50:  6.90nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312574(US9604989, Example 60)
Affinity DataIC50:  7.20nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312534(US9604989, Example 22)
Affinity DataIC50:  8nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312567(1-[4-(6-Methoxy-7,8-dimethyl-3-phenylimidazo[1,2-b...)
Affinity DataIC50:  9.20nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312519(1-[4-(6-Bromo-8-methyloxy-3-phenylimidazo[1,2-b]py...)
Affinity DataIC50:  9.70nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312526(US9604989, Example 14)
Affinity DataIC50:  9.80nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312591(1-[4-(8-Butoxy-6-ethoxy-3-phenylimidazo[1,2-b]pyri...)
Affinity DataIC50:  10nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312539(US9604989, Example 26)
Affinity DataIC50:  10nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312590(US9604989, Example 76)
Affinity DataIC50:  11nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312585(US9604989, Example 71)
Affinity DataIC50:  11nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312578(US9604989, Example 64)
Affinity DataIC50:  12nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312568(1-{4-[7,8-Dimethyl-6-(methylsulfanyl)-3-phenylimid...)
Affinity DataIC50:  12nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312548(US9604989, Example 34)
Affinity DataIC50:  14nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312531(US9604989, Example 19)
Affinity DataIC50:  15nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312566(2-[4-(1-Aminocyclobutyl)phenyl]-7,8-dimethyl-3-phe...)
Affinity DataIC50:  15nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312540(US9604989, Example 27)
Affinity DataIC50:  15nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312576(US9604989, Example 62)
Affinity DataIC50:  16nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312570(Methyl 2-[4-(1-aminocyclobutyl)phenyl]-3-phenyl-8-...)
Affinity DataIC50:  16nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312550(US9604989, Example 36)
Affinity DataIC50:  17nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312534(US9604989, Example 22)
Affinity DataIC50:  18nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312521(1-[4-(6,8-Dimethyloxy-3-phenylimidazo[1,2-b]pyrida...)
Affinity DataIC50:  18nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312517(2-[4-(1-Aminocyclobutyl)phenyl]-3-phenylimidazo[1,...)
Affinity DataIC50:  18nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312585(US9604989, Example 71)
Affinity DataIC50:  20nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312524(US9604989, Example 12)
Affinity DataIC50:  21nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312589(US9604989, Example 75)
Affinity DataIC50:  21nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312582(2-[4-(1-Aminocyclobutyl)phenyl]-N-methyl-3-phenyli...)
Affinity DataIC50:  21nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312590(US9604989, Example 76)
Affinity DataIC50:  23nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312574(US9604989, Example 60)
Affinity DataIC50:  24nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312571(US9604989, Example 57)
Affinity DataIC50:  25nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312566(2-[4-(1-Aminocyclobutyl)phenyl]-7,8-dimethyl-3-phe...)
Affinity DataIC50:  26nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312564(1-[4-(6-Chloro-7,8-dimethyl-3-phenylimidazo[1,2-b]...)
Affinity DataIC50:  27nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM312571(US9604989, Example 57)
Affinity DataIC50:  29nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


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