Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 1265
TargetInsulin-degrading enzyme(Human)
President and Fellows of Harvard College

US Patent
LigandChemical structure of BindingDB Monomer ID 314096BDBM314096(US9610322, 6b (trans olefin))
Affinity DataIC50: 60nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetInsulin-degrading enzyme(Human)
President and Fellows of Harvard College

US Patent
LigandChemical structure of BindingDB Monomer ID 314094BDBM314094(US9610322, 5b (trans olefin))
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetInsulin-degrading enzyme(Human)
President and Fellows of Harvard College

US Patent
LigandChemical structure of BindingDB Monomer ID 314089BDBM314089(US9610322, 3b (trans olefin))
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetInsulin-degrading enzyme(Human)
President and Fellows of Harvard College

US Patent
LigandChemical structure of BindingDB Monomer ID 314095BDBM314095(US9610322, 6a (cis olefin))
Affinity DataIC50: 5.60E+3nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetInsulin-degrading enzyme(Human)
President and Fellows of Harvard College

US Patent
LigandChemical structure of BindingDB Monomer ID 314087BDBM314087(US9610322, 2 (cis olefin))
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetInsulin-degrading enzyme(Human)
President and Fellows of Harvard College

US Patent
LigandChemical structure of BindingDB Monomer ID 314088BDBM314088(US9610322, 3a (cis olefin))
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetInsulin-degrading enzyme(Human)
President and Fellows of Harvard College

US Patent
LigandChemical structure of BindingDB Monomer ID 314093BDBM314093(US9610322, 5a (cis olefin))
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetInsulin-degrading enzyme(Human)
President and Fellows of Harvard College

US Patent
LigandChemical structure of BindingDB Monomer ID 314086BDBM314086(US9610322, 1 (cis olefin))
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetInsulin-degrading enzyme(Human)
President and Fellows of Harvard College

US Patent
LigandChemical structure of BindingDB Monomer ID 314092BDBM314092(US9610322, 4b (trans olefin))
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetInsulin-degrading enzyme(Human)
President and Fellows of Harvard College

US Patent
LigandChemical structure of BindingDB Monomer ID 314090BDBM314090(US9610322, 4a (cis olefin))
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent