Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 1293
TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314813BDBM314813((3aR,5S,6S,7R,7aR)-5-((R)-1-(4- benzylbenzyloxy)-2...)
Affinity DataKi:  0.160nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314809BDBM314809((3aR,5S,6S,7R,7aR)-2-(dimethylamino)-5-((R)-1-meth...)
Affinity DataKi:  0.190nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314781BDBM314781((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  0.450nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314796BDBM314796((3aR,5S,6S,7R,7aR)-2- (methylamino)-5-((R)-2,2,2- ...)
Affinity DataKi:  0.590nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314787BDBM314787((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  0.610nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314778BDBM314778((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  0.650nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314794BDBM314794((3aR,5S,6S,7R,7aR)-2- (methylamino)-5-((R)-2,2,2- ...)
Affinity DataKi:  0.710nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314788BDBM314788((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  0.780nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314750BDBM314750((3aR,5S,6S,7R,7aR)-5-((R)-1-(4-(allyloxy)benzyloxy...)
Affinity DataKi:  0.820nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314780BDBM314780((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  0.840nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314812BDBM314812((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((S)-2,2,2...)
Affinity DataKi:  0.960nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314784BDBM314784((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((S)-1-eth...)
Affinity DataKi:  1.02nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314803BDBM314803((3aR,5S,6S,7R,7aR)-2- (methylamino)-5-((R)-2,2,2- ...)
Affinity DataKi:  1.06nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314779BDBM314779((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  1.11nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314786BDBM314786((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  1.13nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314815BDBM314815((3aR,5S,6S,7R,7aR)-2- (methylamino)-5-((S)-1,1,1- ...)
Affinity DataKi:  1.29nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314783BDBM314783((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((S)-2,2,2...)
Affinity DataKi:  1.32nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314776BDBM314776((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  1.35nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314775BDBM314775((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  1.38nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314797BDBM314797((3aR,5S,6S,7R,7aR)-2- (methylamino)-5-((R)-2,2,2- ...)
Affinity DataKi:  1.44nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314772BDBM314772((3aR,5S,6S,7R,7aR)-5-((R)-1- (2,3-difluorobenzylox...)
Affinity DataKi:  1.44nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314792BDBM314792((3aR,5S,6S,7R,7aR)-5-((R)-1-(2- cyclohexylethoxy)-...)
Affinity DataKi:  1.49nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314766BDBM314766((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  1.52nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314745BDBM314745((3aR,5S,6S,7R,7aR)-2-(dimethylamino)-5-((R)-2,2,2-...)
Affinity DataKi:  1.79nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314771BDBM314771((3aR,5S,6S,7R,7aR)-5-((R)-1-(4- benzylbenzyloxy)-2...)
Affinity DataKi:  1.97nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314782BDBM314782((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  1.98nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314762BDBM314762((3aR,5S,6S,7R,7aR)-5-((R)-1-(2- cyclohexylethoxy)-...)
Affinity DataKi:  2.27nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314785BDBM314785((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  2.32nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314769BDBM314769((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  2.36nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314767BDBM314767((3aR,5S,6S,7R,7aR)-5-((R)-1- (benzyloxy)-2,2,2-tri...)
Affinity DataKi:  2.43nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314758BDBM314758((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  2.85nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314770BDBM314770((3aR,5S,6S,7R,7aR)-5-((R)-1- (biphenyl-4-ylmethoxy...)
Affinity DataKi:  3.05nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314793BDBM314793((3aR,5S,6S,7R,7aR)-2- (methylamino)-5-((R)-2,2,2- ...)
Affinity DataKi:  3.11nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314752BDBM314752(US9611275, Example 21)
Affinity DataKi:  3.31nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314748BDBM314748((3aR,5R,6S,7R,7aR)-5-((S)-1-amino-2,2,2-trifluoroe...)
Affinity DataKi:  3.69nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314791BDBM314791((3aR,5S,6S,7R,7aR)-2- (methylamino)-5-((R)-2,2,2- ...)
Affinity DataKi:  3.77nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314754BDBM314754((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  4.14nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314814BDBM314814((3aR,5S,6S,7R,7aR)-5-((S)-1- methoxyethyl)-2-(meth...)
Affinity DataKi:  4.26nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314804BDBM314804((3aR,5S,6S,7R,7aR)-5-((R)-1-(4- aminophenoxy)-2,2,...)
Affinity DataKi:  4.29nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314743BDBM314743(US9611275, Example 8 | (3aR,5S,6S,7R,7aR)-2-(methy...)
Affinity DataKi:  4.35nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314759BDBM314759((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  4.40nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314753BDBM314753((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  4.5nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314715BDBM314715((3aR,5S,6S,7R,7aR)-2-(dimethylamino)-5-((R)-2,2,2-...)
Affinity DataKi:  4.60nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314761BDBM314761((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  4.85nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314757BDBM314757((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  4.88nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314721BDBM314721((3aR,5S,6S,7R,7aR)-2-(methylamino)-5-((S)-2,2,2-tr...)
Affinity DataKi:  4.98nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314743BDBM314743(US9611275, Example 8 | (3aR,5S,6S,7R,7aR)-2-(methy...)
Affinity DataKi:  5.06nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314807BDBM314807((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((S)-1-(4-...)
Affinity DataKi:  6.73nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314755BDBM314755((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  8.83nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 314774BDBM314774((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...)
Affinity DataKi:  10.3nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

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