Compile Data Set for Download or QSAR
Report error Found 574 Enz. Inhib. hit(s) with all data for entry = 1365
TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318584BDBM318584(US9624241, Example 128 | 3-[7-(3,5-Dimethylisoxazo...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318583BDBM318583(US9624241, Example 127 | 3-[7-(3,5-Dimethylisoxazo...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318584BDBM318584(US9624241, Example 128 | 3-[7-(3,5-Dimethylisoxazo...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318586BDBM318586(US9624241, Example 130 | 4-[2-(Aminomethyl)pyridin...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318585BDBM318585(US9624241, Example 129 | 3-[7-(3,5-Dimethylisoxazo...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318587BDBM318587(US9624241, Example 131 | N-({3-[7-(3,5-Dimethyliso...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318586BDBM318586(US9624241, Example 130 | 4-[2-(Aminomethyl)pyridin...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318579BDBM318579(US9624241, Example 123 | 7-(3,5-Dimethylisoxazol-4...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318581BDBM318581(US9624241, Example 125 | 7-[5-(Fluoromethyl)-3-met...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318583BDBM318583(US9624241, Example 127 | 3-[7-(3,5-Dimethylisoxazo...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318582BDBM318582(US9624241, Example 126 | 3-[7-(3,5-Dimethylisoxazo...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318592BDBM318592(US9624241, Example 136 | 3-[7-(3,5-dimethylisoxazo...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318591BDBM318591(US9624241, Example 135 | 3-[7-(3,5-Dimethylisoxazo...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318592BDBM318592(US9624241, Example 136 | 3-[7-(3,5-dimethylisoxazo...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318594BDBM318594(US9624241, Example 138 | N-{[(4S)-7-(3,5-Dimethyli...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318593BDBM318593(US9624241, Example 137 | (4S)-9-(Aminomethyl)-7-(3...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318595BDBM318595(US9624241, Example 139 | N-{[(4S)-7-(3,5-Dimethyli...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318594BDBM318594(US9624241, Example 138 | N-{[(4S)-7-(3,5-Dimethyli...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318588BDBM318588(US9624241, Example 132 | Methyl 3-[7-(3,5-dimethyl...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318587BDBM318587(US9624241, Example 131 | N-({3-[7-(3,5-Dimethyliso...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318589BDBM318589(US9624241, Example 133 | Single enantiomer of 3-[7...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318588BDBM318588(US9624241, Example 132 | Methyl 3-[7-(3,5-dimethyl...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318590BDBM318590(US9624241, Example 134 | N-Cyclopropyl-3-[7- (3,5-...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318589BDBM318589(US9624241, Example 133 | Single enantiomer of 3-[7...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318591BDBM318591(US9624241, Example 135 | 3-[7-(3,5-Dimethylisoxazo...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318590BDBM318590(US9624241, Example 134 | N-Cyclopropyl-3-[7- (3,5-...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318599BDBM318599(US9624241, Example 143 | 2-(Dimethylamino)-N-{[(4S...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318600BDBM318600(US9624241, Example 144A | (4S)-7-(3,5-dimethylisox...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318602BDBM318602(US9624241, Example 145 | (3R)-1-[(4S)-7-(3,5-Dimet...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318601BDBM318601(US9624241, Example 144B | US10464947, Example 144B...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318603BDBM318603(US9624241, Example 146A | 1-[(4S)-7-(3,5-Dimethyli...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318602BDBM318602(US9624241, Example 145 | (3R)-1-[(4S)-7-(3,5-Dimet...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318596BDBM318596(US9624241, Example 140 | N-{[(4S)-7-(3,5-Dimethyli...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318595BDBM318595(US9624241, Example 139 | N-{[(4S)-7-(3,5-Dimethyli...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318597BDBM318597(US9624241, Example 141 | N-{[(4S)-7-(3,5-Dimethyli...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318596BDBM318596(US9624241, Example 140 | N-{[(4S)-7-(3,5-Dimethyli...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318597BDBM318597(US9624241, Example 141 | N-{[(4S)-7-(3,5-Dimethyli...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318598BDBM318598(US9624241, Example 142 | N-{[(4S)-7-(3,5-Dimethyli...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318608BDBM318608(US9624241, Example 149 | (4S)-7-(3,5-Dimethylisoxa...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318607BDBM318607(US9624241, Example 148 | (4S)-2-(4-Acetyl-1,4-diaz...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318609BDBM318609(US9624241, Example 150 | (4S)-7-(3,5-Dimethylisoxa...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318608BDBM318608(US9624241, Example 149 | (4S)-7-(3,5-Dimethylisoxa...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318610BDBM318610(US9624241, Example 151 | 2-{4-[(4S)-7-(3,5-Dimethy...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318609BDBM318609(US9624241, Example 150 | (4S)-7-(3,5-Dimethylisoxa...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318611BDBM318611(US9624241, Example 152 | 2-Cyano-N-{(3R)-1-[(4S)-7...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318610BDBM318610(US9624241, Example 151 | 2-{4-[(4S)-7-(3,5-Dimethy...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318604BDBM318604(US9624241, Example 146B | 1-[(4S)-7-(3,5-Dimethyli...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318603BDBM318603(US9624241, Example 146A | 1-[(4S)-7-(3,5-Dimethyli...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318605BDBM318605(US9624241, Example 146C | 1-[(4S)-7-(3,5-Dimethyli...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 318604BDBM318604(US9624241, Example 146B | 1-[(4S)-7-(3,5-Dimethyli...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

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