Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 1438
TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323106BDBM323106(US9630931, Example 4)
Affinity DataIC50: 0.0500nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323107BDBM323107(US9630931, Example 5)
Affinity DataIC50: 0.0600nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 316493BDBM316493(US9630931, Example 2)
Affinity DataIC50: 0.0900nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 316492BDBM316492(US9630931, Example 1)
Affinity DataIC50: 0.100nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323143BDBM323143(US9630931, Example 6)
Affinity DataIC50: 0.100nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323098BDBM323098(US9630931, Example 3)
Affinity DataIC50: 0.140nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323169BDBM323169(US9630931, Example 27)
Affinity DataIC50: 0.210nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323150BDBM323150(US9630931, Example 13)
Affinity DataIC50: 0.270nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323148BDBM323148(US9630931, Example 11)
Affinity DataIC50: 0.280nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323151BDBM323151(US9630931, Example 14)
Affinity DataIC50: 0.400nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323170BDBM323170(US9630931, Example 28)
Affinity DataIC50: 0.480nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323156BDBM323156(US9630931, Example 18)
Affinity DataIC50: 0.520nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323168BDBM323168(US9630931, Example 26)
Affinity DataIC50: 0.580nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323167BDBM323167(US9630931, Example 25)
Affinity DataIC50: 0.610nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323147BDBM323147(US9630931, Example 10)
Affinity DataIC50: 0.650nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323146BDBM323146(US9630931, Example 9)
Affinity DataIC50: 0.690nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323145BDBM323145(US9630931, Example 8)
Affinity DataIC50: 0.75nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323144BDBM323144(US9630931, Example 7)
Affinity DataIC50: 0.800nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323166BDBM323166(US9630931, Example 24)
Affinity DataIC50: 1.10nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323159BDBM323159(US9630931, Example 19)
Affinity DataIC50: 1.90nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323171BDBM323171(US9630931, Example 30)
Affinity DataIC50: 2.90nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323161BDBM323161(US9630931, Example 20)
Affinity DataIC50: 7.10nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323163BDBM323163(US9630931, Example 22)
Affinity DataIC50: 8.20nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323162BDBM323162(US9630931, Example 21)
Affinity DataIC50: 10nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323155BDBM323155(US9630931, Example 17)
Affinity DataIC50: 13nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323165BDBM323165(US9630931, Example 23)
Affinity DataIC50: 19nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323153BDBM323153(US9630931, Example 15)
Affinity DataIC50: 20nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323149BDBM323149(US9630931, Example 12)
Affinity DataIC50: 30nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandChemical structure of BindingDB Monomer ID 323154BDBM323154(US9630931, Example 16)
Affinity DataIC50: 76nMAssay Description:Reaction Buffer:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOReq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
US Patent