Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 1510
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM327854(2-[8-fluoro-2-[2- (hydroxymethyl)-3-[5- [[5-(1-hyd...)
Affinity DataIC50: 1.12nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of BTK, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM327860(8-tert-butyl-4-[2- (hydroxymethyl)-3-[1- methyl-5-...)
Affinity DataIC50: 1.77nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of BTK, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM327861(8-tert-butyl-4-[2- (hydroxymethyl)-3-[1- methyl-5-...)
Affinity DataIC50: 4.24nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of BTK, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM327859(6-tert-butyl-8-fluoro- 2-[2-methyl-3-[1- methyl-5-...)
Affinity DataIC50: 6.5nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of BTK, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM327853(2-[2-[2- (hydroxymethyl)-3-[1- methyl-5-[[5- (morp...)
Affinity DataIC50: 11.2nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of BTK, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM327857(6-tert-butyl-2-[2- (hydroxymethyl)-3-[1- methyl-5-...)
Affinity DataIC50: 13.7nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of BTK, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM327858(6-tert-butyl-2-[2- (hydroxymethyl)-3-[1- methyl-5-...)
Affinity DataIC50: 14.6nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of BTK, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM327856(5-chloro-N-[2- (hydroxymethyl)-3-[1- methyl-5-[[5-...)
Affinity DataIC50: 31.9nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of BTK, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM327855(4-[2- (hydroxymethyl)-3-[1- methyl-5-[(5- methylsu...)
Affinity DataIC50: 52.6nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of BTK, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent