Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 1518
TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329334((2R)-2-(4-fluorophenyl)-N-[4-(2-{[2-methoxy-4-(met...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329335((2R)—N-[4-(2-{[2-ethoxy-4-(methylsulfonyl)phe...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329358((2R)-2-amino-2-(4-fluorophenyl)-N-[4-(2-{[4-(pyrro...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329357((2R)-2-amino-N-{4-[2-({4-[(3-fluoroazetidin-1-yl)c...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329336((2R)-2-(4-fluorophenyl)-N-[4-(2-{[4-(methylsulfony...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329337(4-{[6-(4-{[(2R)-2-(4-fluorophenyl)propanoyl]amino}...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329338(4-{[6-(4-{[2R)-2-(4-fluorophenyl)propanoyl]amino}p...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329339(4-{[6-(4-{[(2R)-2-(4-fluorophenyl)propanoyl]amino}...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329340((2R)—N-{4-[2-({4-[(3-fluoroazetidin-1-yl)carb...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329341((2R)—N-[4-(2-{[4-(azetidin-1-ylcarbonyl)-2-me...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329342((2R)-2-(4-fluorophenyl)-N-[4-(2-{[2-methoxy-4-(2-o...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329343((−)-2-(4-fluorophenyl)-3-hydroxy-N-[4-(2-{[4...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329344((2R)-2-amino-2-(4-fluorophenyl)-N-[4-(2-{[2-methox...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329345(4-{[6-(4-{[(2R)-2-(4-fluorophenyl)propanoyl]amino}...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329346((2R)-2-(4-fluorophenyl)-N-[4-(2-{[2-methoxy-4-(pyr...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329347((2R)—N-{4-[2-({4-[(3-fluoroazetidin-1-yl)carb...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329348((2R)-2-(4-fluorophenyl)-N-{4-[2-({4-[(3-hydroxyaze...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329349((2R)-2-(4-fluorophenyl)-N-[4-(2-{[4-(pyrrolidin-1-...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329350((2S)-2-(4-fluorophenyl)-3-hydroxy-N-[4-(2-{[2-meth...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329351((2S)—N-{4-[2-({4-[(3-fluoroazetidin-1-yl)carb...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329352((2R)-2-amino-2-(4-fluorophenyl)-N-[4-(2-{[4-(methy...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329353((2R)-2-amino-2-(4-fluorophenyl)-N-[4-(2-{[2-methox...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329354((2R)-2-amino-N-{4-[2-({4-[(3-fluoroazetidin-1-yl)c...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329355((2R)-2-amino-N-[4-(2-{[4-(azetidin-1-ylcarbonyl)-2...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329356((2R)-2-amino-2-(4-fluorophenyl)-N-[4-(2-{[2-methox...)
Affinity DataIC50: <1nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329359(US9663510, Example comparitive example 2)
Affinity DataIC50:  11nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329360(US9663510, Example comparitive example disclosed i...)
Affinity DataIC50:  13nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetDual specificity protein kinase TTK(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329361(US9663510, Example comparitive example 4)
Affinity DataIC50:  15nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent