Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 148
TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193676BDBM193676(US9670208, Example 295 4-(3-(cyclopropylmethyl)-[1...)
Affinity DataIC50: 0.400nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193385BDBM193385(US9670208, Example 57)
Affinity DataIC50: 0.5nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193675BDBM193675(US9670208, Example 279 N-(1-methyl-1H-pyrazol-5-yl...)
Affinity DataIC50: 0.600nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193773BDBM193773(US9670208, Example 402 4-(3-(4-fluorobenzyl)-[1,2,...)
Affinity DataIC50: 0.600nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 191370BDBM191370(US9670208, Example 35)
Affinity DataIC50: 0.800nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193672BDBM193672(US9670208, Example 278 4-(3-(pyridin-2-ylmethyl)-[...)
Affinity DataIC50: 0.800nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193781BDBM193781(US9670208, Example 493 4-(3-((6-ethoxypyridin-3-yl...)
Affinity DataIC50: 0.800nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193381BDBM193381(US9670208, Example 49)
Affinity DataIC50: 0.800nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193396BDBM193396(US9670208, Example 121)
Affinity DataIC50: 0.900nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193412BDBM193412(US9670208, Example 276 N-(1-methyl-1H-pyrazol-5-yl...)
Affinity DataIC50: 0.900nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193410BDBM193410(US9670208, Example 272 4-(3-((6-methoxypyridin-3-y...)
Affinity DataIC50: 0.900nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193776BDBM193776(US9670208, Example 403 4-(3-(3-fluoro-4-methoxyben...)
Affinity DataIC50: 0.900nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193756BDBM193756(US9670208, Example 317 4-(3-((4,4-difluorocyclohex...)
Affinity DataIC50: 0.900nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193411BDBM193411(US9670208, Example 275 N-(1-methyl-1H-pyrazol-5-yl...)
Affinity DataIC50: 1.5nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193754BDBM193754(US9670208, Example 306 N-(1-methyl-1H-pyrazol-5-yl...)
Affinity DataIC50: 1.80nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193780BDBM193780(US9670208, Example 467 N-(1-(3-chloro-4-fluorophen...)
Affinity DataIC50: 1.80nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193404BDBM193404(US9670208, Example 163 4-(3-(bicyclo[2.2.1]heptan-...)
Affinity DataIC50: 2.40nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193758BDBM193758(US9670208, Example 379 4-(3-((1s,3s)-adamantan-1-y...)
Affinity DataIC50: 2.40nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193384BDBM193384(US9670208, Example 51)
Affinity DataIC50: 2.60nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193405BDBM193405(US9670208, Example 169 4-(3-isobutyl-[1,2,4]triazo...)
Affinity DataIC50: 2.70nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193397BDBM193397(US9670208, Example 123)
Affinity DataIC50: 2.80nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193392BDBM193392(US9670208, Example 115)
Affinity DataIC50: 2.80nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193386BDBM193386(US9670208, Example 67)
Affinity DataIC50: 2.80nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193403BDBM193403(US9670208, Example 150 N-(1-methyl-1H-pyrazol-5-yl...)
Affinity DataIC50: 2.80nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193389BDBM193389(US9670208, Example 111)
Affinity DataIC50: 2.90nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193772BDBM193772(US9670208, Example 398 4-(3-(2-fluorobenzyl)-[1,2,...)
Affinity DataIC50: 3nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193387BDBM193387(US9670208, Example 84)
Affinity DataIC50: 3.20nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193394BDBM193394(US9670208, Example 116)
Affinity DataIC50: 3.30nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193770BDBM193770(US9670208, Example 396 N-(1-methyl-1H-pyrazol-5-yl...)
Affinity DataIC50: 3.30nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193380BDBM193380(US9670208, Example 40)
Affinity DataIC50: 3.30nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193391BDBM193391(US9670208, Example 113)
Affinity DataIC50: 3.40nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193388BDBM193388(US9670208, Example 108)
Affinity DataIC50: 3.40nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193755BDBM193755(US9670208, Example 307 4-(3-((cyclopentylthio)meth...)
Affinity DataIC50: 3.5nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193757BDBM193757(US9670208, Example 377 4-(3-((dimethylamino)(4-flu...)
Affinity DataIC50: 5.40nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193409BDBM193409(US9670208, Example 258 (E)-4-(3-(but-1-en-1-yl)-[1...)
Affinity DataIC50: 5.70nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193406BDBM193406(US9670208, Example 192 4-(3-(isochroman-1-yl)-[1,2...)
Affinity DataIC50: 6nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193402BDBM193402(US9670208, Example 140 (2,6-difluorophenyl)(2-(7-(...)
Affinity DataIC50: 7.5nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193777BDBM193777(US9670208, Example 411 4-([1,2,4]triazolo[4,3-a]py...)
Affinity DataIC50: 11nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193390BDBM193390(US9670208, Example 112)
Affinity DataIC50: 17nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193407BDBM193407(US9670208, Example 195 (S)-4-(3-(methoxy(phenyl)me...)
Affinity DataIC50: 25nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193769BDBM193769(US9670208, Example 387 4-(3-(morpholin-2-yl)-[1,2,...)
Affinity DataIC50: 117nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193778BDBM193778(US9670208, Example 419 4-(3-(1-(4-fluorophenyl)-5-...)
Affinity DataIC50: 135nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193401BDBM193401(US9670208, Example 136 1-methyl-4-phenyl-5-(7-(2-(...)
Affinity DataIC50: 171nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193782BDBM193782(US9670208, Example 512 (7-(2-((1-methyl-1H-pyrazol...)
Affinity DataIC50: 172nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193408BDBM193408(US9670208, Example 211 4-(3-(2-fluorobenzyl)-[1,2,...)
Affinity DataIC50: 172nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193400BDBM193400(US9670208, Example 132 4-(3-(1-((5-fluoro-2-methox...)
Affinity DataIC50: 197nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193398BDBM193398(US9670208, Example 131 4-(3-(piperidin-3-yl)-[1,2,...)
Affinity DataIC50: 224nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 193783BDBM193783(US9670208, Example 563 2-cyclopropyl-1-(7-(2-((1-m...)
Affinity DataIC50: 661nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent