Compile Data Set for Download or QSAR
Report error Found 112 Enz. Inhib. hit(s) with all data for entry = 122
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180912BDBM180912(US9676721, 28 2-cyano-1-({4-[(3,4-difluorobenzene)...)
Affinity DataIC50: 0.800nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180915BDBM180915(US9676721, 21 1-{2-[4-(benzenesulfonyl)phenyl]ethy...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180918BDBM180918(US9676721, 36 2-cyano-1-({4-[(3-fluoro-4-methoxybe...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180067BDBM180067(US9676721, 17 1-[(4-{[4-chloro-3-(trifluoromethyl)...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180928BDBM180928(US9676721, 97 2-cyano-3-(pyridin-4-yl)-1-{[4-(quin...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180103BDBM180103(US9676721, 32 2-cyano-1-({4-[(3,5-difluorobenzene)...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180921BDBM180921(US9676721, 79 2-cyano-1-{[4-(1-methyl-1H-indazole-...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 181033BDBM181033(US9676721, 41 2-cyano-1-({4-[(3-methoxy-4-methylbe...)
Affinity DataIC50: 1.20nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180064BDBM180064(US9676721, 64 2-cyano-1-[(4-{[3-(dimethylsulfamoyl...)
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180081BDBM180081(US9676721, 88 2-cyano-1-{[4-(6-methylpyridine-3-su...)
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 181032BDBM181032(US9676721, 75 2-cyano-1-[(4-{[4-(morpholin-4-yl)be...)
Affinity DataIC50: 1.5nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180272BDBM180272(US9676721, 42 2-cyano-1-({4-[(3-methoxybenzene)sul...)
Affinity DataIC50: 1.5nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180920BDBM180920(US9676721, 39 2-cyano-1-({4-[(3-fluoro-5-methylben...)
Affinity DataIC50: 1.70nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180786BDBM180786(US9676721, 34 2-cyano-1-({4-[(3-cyanobenzene)sulfo...)
Affinity DataIC50: 1.70nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180257BDBM180257(US9676721, 78 2-cyano-1-{[4-({3-[(morpholin-4-yl)c...)
Affinity DataIC50: 1.70nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180095BDBM180095(US9676721, 27 2-cyano-1-({4-[(3,4-dichlorobenzene)...)
Affinity DataIC50: 1.70nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180101BDBM180101(US9676721, 20 1-{[4-(2H-1,3-benzodioxole-5-sulfony...)
Affinity DataIC50: 1.80nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180049BDBM180049(US9676721, 65 2-cyano-1-[(4-{[3-(ethanesulfonyl)be...)
Affinity DataIC50: 1.80nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180089BDBM180089(US9676721, 57 2-cyano-1-({4-[6-(morpholin-4-yl)pyr...)
Affinity DataIC50: 1.90nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180260BDBM180260(US9676721, 4 1-({4-[(3-chloro-4-methylbenzene)sulf...)
Affinity DataIC50: 1.90nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 181022BDBM181022(US9676721, 108 3-{[4-(benzenesulfonyl)phenyl]methy...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 181671BDBM181671(US9676721, 11 1-({4-[(4-chloro-3-fluorobenzene)sul...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180253BDBM180253(US9676721, 90 2-cyano-3-({4-[(4-fluorobenzene)sulf...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180854BDBM180854(US9676721, 69 2-cyano-1-[(4-{[3-(propane-1-sulfona...)
Affinity DataIC50: 2.10nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 181024BDBM181024(US9676721, 80 2-cyano-1-{[4-(1-methyl-1H-indole-2-...)
Affinity DataIC50: 2.10nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180083BDBM180083(US9676721, 30 2-cyano-1-({4-[(3,4-dimethylbenzene)...)
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180868BDBM180868(US9676721, 106 3-[(4-{[2-cyano-3-(pyridin-4-yl)car...)
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180255BDBM180255(US9676721, 38 2-cyano-1-({4-[(3-fluoro-5-methoxybe...)
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180122BDBM180122(US9676721, 85 2-cyano-1-{[4-(4-methylpyridine-3-su...)
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 181669BDBM181669(US9676721, 23 2-cyano-1-({4-[(2,4-dimethylbenzene)...)
Affinity DataIC50: 2.40nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180922BDBM180922(US9676721, 53 2-cyano-1-({4-[(4-methylbenzene)sulf...)
Affinity DataIC50: 2.5nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 181031BDBM181031(US9676721, 92 2-cyano-3-(pyridin-4-yl)-1-[(4-{[3-(...)
Affinity DataIC50: 2.5nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180091BDBM180091(US9676721, 3 1-({4-[(3-chloro-4-methoxybenzene)sul...)
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180065BDBM180065(US9676721, 1 (E)-3-({4-[(3-chlorobenzene)sulfonyl]...)
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180094BDBM180094(US9676721, 77 2-cyano-1-[(4-{[4-(propan-2-yloxy)be...)
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180919BDBM180919(US9676721, 54 2-cyano-1-({4-[(4-phenylbenzene)sulf...)
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180092BDBM180092(US9676721, 67 2-cyano-1-[(4-{[3-(propan-2-yl)benze...)
Affinity DataIC50: 2.90nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180102BDBM180102(US9676721, 99 2-cyano-3-(pyridin-4-yl)-1-{[4-(quin...)
Affinity DataIC50: 2.90nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180917BDBM180917(US9676721, 100 2-cyano-3-[(4-{8-oxa-3-azabicyclo[3...)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 181028BDBM181028(US9676721, 63 2-cyano-1-[(4-{[3-(3,5-dimethyl-1H-p...)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180259BDBM180259(US9676721, 10 1-({4-[(4-chloro-2-methoxybenzene)su...)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180258BDBM180258(US9676721, 49 2-cyano-1-({4-[(4-fluoro-3-methylben...)
Affinity DataIC50: 3.10nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180927BDBM180927(US9676721, 40 2-cyano-1-({4-[(3-fluorobenzene)sulf...)
Affinity DataIC50: 3.20nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180126BDBM180126(US9676721, 68 2-cyano-1-[(4-{[3-(propan-2-yloxy)be...)
Affinity DataIC50: 3.20nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180254BDBM180254(US9676721, 8 1-({4-[(3-chloro-5-methylbenzene)sulf...)
Affinity DataIC50: 3.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180256BDBM180256(US9676721, 33 2-cyano-1-({4-[(3,5-dimethylbenzene)...)
Affinity DataIC50: 3.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 181670BDBM181670(US9676721, 16 1-[(4-{[3-chloro-5-(trifluoromethyl)...)
Affinity DataIC50: 3.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180252BDBM180252(US9676721, 74 2-cyano-1-[(4-{[4-(1H-pyrazol-1-yl)b...)
Affinity DataIC50: 3.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180123BDBM180123(US9676721, 104 3-[(4-{[2-cyano-3-(pyridin-4-yl)car...)
Affinity DataIC50: 3.40nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Forma Tm

US Patent
LigandChemical structure of BindingDB Monomer ID 180106BDBM180106(US9676721, 15 1-({4-[3-chloro-2-(morpholin-4-yl)py...)
Affinity DataIC50: 3.40nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

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