Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 124
TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182893BDBM182893(US9676732, 27 3-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  16nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182905BDBM182905(US9676732, 39 6-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  17nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182906BDBM182906(US9676732, 40 6-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  23nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182929BDBM182929(US9676732, 63 5-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  26nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182890BDBM182890(US9676732, 24 3-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  26nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182894BDBM182894(US9676732, 28 3-[2,6-Difluoro-4-[2-(3-pyridyl)ethy...)
Affinity DataEC50:  29nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182901BDBM182901(US9676732, 35 6-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  30nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182931BDBM182931(US9676732, 65 3-[2-Chloro-4-(2-phenylethynyl)pheny...)
Affinity DataEC50:  32nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182898BDBM182898(US9676732, 32 6-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  33nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182924BDBM182924(US9676732, 58 6-[2-Chloro-6-fluoro-4-[2-(3-pyridyl...)
Affinity DataEC50:  37nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182936BDBM182936(US9676732, 70 3-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  38nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182899BDBM182899(US9676732, 33 6-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  47nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182934BDBM182934(US9676732, 68 3-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  48nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182935BDBM182935(US9676732, 69 1-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  50nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182886BDBM182886(US9676732, 20 3-[2-Chloro-4-(2-phenylethynyl)pheny...)
Affinity DataEC50:  50nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182887BDBM182887(US9676732, 21 3-[2-Chloro-4-(2-phenylethynyl)pheny...)
Affinity DataEC50:  52nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182895BDBM182895(US9676732, 29 2-(2,6-Difluoro-4-(phenylethynyl)phe...)
Affinity DataEC50:  52nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182879BDBM182879(US9676732, 13 3-[2-Chloro-4-(2-phenylethynyl)pheny...)
Affinity DataEC50:  57nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182940BDBM182940(US9676732, 74 8-(2,2-Difluoroethoxy)-3-[2,6-difluo...)
Affinity DataEC50:  60nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182938BDBM182938(US9676732, 72 3-[2-Fluoro-4-(2-phenylethynyl)-6-(t...)
Affinity DataEC50:  63nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182923BDBM182923(US9676732, 57 6-[2,6-Difluoro-4-[2-(3-pyridyl)ethy...)
Affinity DataEC50:  65nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182874BDBM182874(US9676732, 8 3-[2-Chloro-4-(2-phenylethynyl)phenyl...)
Affinity DataEC50:  65nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182900BDBM182900(US9676732, 34 6-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  74nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182909BDBM182909(US9676732, 43 3-[2-Chloro-6-fluoro-4-[2-(3-pyridyl...)
Affinity DataEC50:  74nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182932BDBM182932(US9676732, 66 3-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  75nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182878BDBM182878(US9676732, 12 2-(2-Chloro-4-(phenylethynyl)phenyl)...)
Affinity DataEC50:  80nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182908BDBM182908(US9676732, 42 3-[2-Chloro-6-fluoro-4-[2-(3-pyridyl...)
Affinity DataEC50:  83nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182937BDBM182937(US9676732, 71 3-[2-Chloro-6-fluoro-4-[2-(3-pyridyl...)
Affinity DataEC50:  86nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182903BDBM182903(US9676732, 37 3-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  88nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182891BDBM182891(US9676732, 25 3-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  89nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182896BDBM182896(US9676732, 30 2-(2,6-Difluoro-4-(pyridin-3-ylethyn...)
Affinity DataEC50:  91nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182927BDBM182927(US9676732, 61 8-Chloro-3-[2,6-difluoro-4-(2-phenyl...)
Affinity DataEC50:  91nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182871BDBM182871(US9676732, 5 3-[2-Chloro-4-(2-phenylethynyl)phenyl...)
Affinity DataEC50:  93nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182868BDBM182868(US9676732, 2 3-[2-Chloro-4-(2-phenylethynyl)phenyl...)
Affinity DataEC50:  94nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182919BDBM182919(US9676732, 53 3-[2-Chloro-4-(2-phenylethynyl)pheny...)
Affinity DataEC50:  102nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182904BDBM182904(US9676732, 38 3-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  108nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182881BDBM182881(US9676732, 15 3-[2-Chloro-4-(2-phenylethynyl)pheny...)
Affinity DataEC50:  110nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182892BDBM182892(US9676732, 26 3-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  115nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182930BDBM182930(US9676732, 64 5-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  121nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182922BDBM182922(US9676732, 56 6-[3-Fluoro-5-(2-phenylethynyl)-2-py...)
Affinity DataEC50:  121nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182885BDBM182885(US9676732, 19 3-[2-Chloro-4-(2-phenylethynyl)pheny...)
Affinity DataEC50:  134nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182869BDBM182869(US9676732, 3 8-Chloro-3-[2-chloro-4-(2-phenylethyn...)
Affinity DataEC50:  137nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182928BDBM182928(US9676732, 62 5-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  137nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182911BDBM182911(US9676732, 45 3-[3-Chloro-5-(2-phenylethynyl)-2-py...)
Affinity DataEC50:  137nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182912BDBM182912(US9676732, 46 3-[3-Chloro-5-(2-phenylethynyl)-2-py...)
Affinity DataEC50:  141nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182883BDBM182883(US9676732, 17 3-[2-Chloro-4-(2-phenylethynyl)pheny...)
Affinity DataEC50:  143nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182884BDBM182884(US9676732, 18 3-[2-Chloro-4-(2-phenylethynyl)pheny...)
Affinity DataEC50:  148nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182867BDBM182867(US9676732, 1 3-[2-Chloro-4-(2-phenylethynyl)phenyl...)
Affinity DataEC50:  150nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182882BDBM182882(US9676732, 16 3-[2-Chloro-4-(2-phenylethynyl)pheny...)
Affinity DataEC50:  152nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 182939BDBM182939(US9676732, 73 3-[2,6-Difluoro-4-[2-(3-pyridyl)ethy...)
Affinity DataEC50:  154nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

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