Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 164
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199331BDBM199331(US9676818, 48)
Affinity DataEC50:  61.5nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199436BDBM199436(US9676818, 82)
Affinity DataEC50:  182nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199112BDBM199112(US9676818, 23)
Affinity DataEC50:  225nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199332BDBM199332(US9676818, 52)
Affinity DataEC50:  279nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199330BDBM199330(US9676818, 45)
Affinity DataEC50:  323nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199461BDBM199461(US9676818, 83)
Affinity DataEC50:  345nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199302BDBM199302(US9676818, 27)
Affinity DataEC50:  518nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199435BDBM199435(US9676818, 66)
Affinity DataEC50:  808nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 50386534BDBM50386534(CHEMBL2048075 | US9676818, 11d)
Affinity DataEC50:  1.01E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199434BDBM199434(US9676818, 65)
Affinity DataEC50:  1.13E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199309BDBM199309(US9676818, 28)
Affinity DataEC50:  1.27E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199462BDBM199462(US9676818, 84)
Affinity DataEC50:  1.50E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 50386538BDBM50386538(CHEMBL2048076 | US9676818, 11e)
Affinity DataEC50:  1.64E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199102BDBM199102(US9676818, chem-us-00156)
Affinity DataEC50:  2.97E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199463BDBM199463(US9676818, 85)
Affinity DataEC50:  3.08E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 50358550BDBM50358550(CHEMBL1923549 | US9676818, 6d)
Affinity DataEC50:  3.63E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 50386537BDBM50386537(CHEMBL2048077 | US9676818, 11f)
Affinity DataEC50:  3.80E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 50386535BDBM50386535(CHEMBL2048219 | US9676818, 11h)
Affinity DataEC50:  4.45E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199481BDBM199481(US9676818, 89)
Affinity DataEC50:  4.78E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 50386539BDBM50386539(CHEMBL2048067 | US9676818, 6e)
Affinity DataEC50:  4.79E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199104BDBM199104(US9676818, 14b)
Affinity DataEC50:  5.47E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 50386536BDBM50386536(CHEMBL2048220 | US9676818, 16)
Affinity DataEC50:  5.52E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199106BDBM199106(US9676818, 14c)
Affinity DataEC50:  5.95E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199114BDBM199114(US9676818, 25)
Affinity DataEC50:  6.81E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199116BDBM199116(US9676818, 26)
Affinity DataEC50:  7.10E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199475BDBM199475(US9676818, 88)
Affinity DataEC50:  9.52E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199327BDBM199327(US9676818, 34)
Affinity DataEC50:  1.18E+4nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199473BDBM199473(US9676818, 86)
Affinity DataEC50:  1.29E+4nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199474BDBM199474(US9676818, 87)
Affinity DataEC50:  2.07E+4nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199433BDBM199433(US9676818, 54)
Affinity DataEC50:  2.21E+5nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199329BDBM199329(US9676818, 41)
Affinity DataEC50:  2.60E+5nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 199328BDBM199328(US9676818, 38)
Affinity DataEC50:  6.41E+5nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent