Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 71
TargetRho-associated protein kinase 2(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148414BDBM148414(US9682963, 7)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO. Required cofactor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148413BDBM148413(US9682963, 6)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO. Required cofactor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148416BDBM148416(US9682963, 9)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO. Required cofactor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148415BDBM148415(US9682963, 8)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO. Required cofactor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148409BDBM148409(US9682963, 3)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO. Required cofactor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148408BDBM148408(US9682963, 2)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO. Required cofactor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148412BDBM148412(US9682963, 5)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO. Required cofactor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148410BDBM148410(US9682963, 4)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO. Required cofactor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148427BDBM148427(US9682963, 15)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO. Required cofactor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148426BDBM148426(US9682963, 14)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO. Required cofactor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148428BDBM148428(US9682963, 16)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO. Required cofactor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148421BDBM148421(US9682963, 11)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO. Required cofactor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148420BDBM148420(US9682963, 10)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO. Required cofactor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148425BDBM148425(US9682963, 13)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO. Required cofactor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148423BDBM148423(US9682963, 12)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO. Required cofactor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148412BDBM148412(US9682963, 5)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148410BDBM148410(US9682963, 4)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148408BDBM148408(US9682963, 2)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148425BDBM148425(US9682963, 13)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148423BDBM148423(US9682963, 12)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148421BDBM148421(US9682963, 11)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148416BDBM148416(US9682963, 9)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148414BDBM148414(US9682963, 7)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148413BDBM148413(US9682963, 6)
Affinity DataEC50: <100nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148407BDBM148407(US9682963, 1)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO. Required cofactor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148409BDBM148409(US9682963, 3)
Affinity DataEC50:  550nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148407BDBM148407(US9682963, 1)
Affinity DataEC50:  550nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

TargetRho-associated protein kinase 1/2(Rat)
Redx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 148415BDBM148415(US9682963, 8)
Affinity DataEC50:  550nMAssay Description:Rat smooth muscle cell line A7r5 is used. The endogenous expression of ROCK results in a constitutive phosphorylation of the regulatory myosin light ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent