Compile Data Set for Download or QSAR
Report error Found 278 Enz. Inhib. hit(s) with all data for entry = 110
TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175901BDBM175901(US9688684, Compound 98: 7-Benzyl-8-(4-butoxy-pheny...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175900BDBM175900(US9688684, Compound 97: 8-(4-Chloro-phenyl)-7-(3-m...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175967BDBM175967(US9688684, Compound 164: [4-(7-Benzyl-5,6,7,8-tetr...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175820BDBM175820(US9688684, Compound 17: {4-[7-(3-Fluoro-benzyl)-5,...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175866BDBM175866(US9688684, Compound 63: 7-(2,3-Difluoro-benzyl)-8-...)
Affinity DataIC50: 500nMAssay Description:For the assay 12,500 293T cells (DSMZ no ACC 635) per 384 well are seeded in 30 μl inMEM Eagle medium, supplemented with 10% FBS, 2 mM Glutamax,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175966BDBM175966(US9688684, Compound 163: 7-(3-Bromo-benzyl)-8-(3-f...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175899BDBM175899(US9688684, Compound 96: 7-(3-Bromo-benzyl)-8-(4-fl...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175965BDBM175965(US9688684, Compound 162: 8-(1-Benzyl-3-isopropyl-1...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175817BDBM175817(US9688684, Compound 14: {4-[7-(2-Fluoro-benzyl)-5,...)
Affinity DataIC50: 500nMAssay Description:For the assay 12,500 293T cells (DSMZ no ACC 635) per 384 well are seeded in 30 μl inMEM Eagle medium, supplemented with 10% FBS, 2 mM Glutamax,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175899BDBM175899(US9688684, Compound 96: 7-(3-Bromo-benzyl)-8-(4-fl...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175864BDBM175864(US9688684, Compound 61: 8-(3-Isopropyl-1-phenyl-1H...)
Affinity DataIC50: 500nMAssay Description:For the assay 12,500 293T cells (DSMZ no ACC 635) per 384 well are seeded in 30 μl inMEM Eagle medium, supplemented with 10% FBS, 2 mM Glutamax,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175903BDBM175903(US9688684, Compound 100: 7-Benzyl-8-m-tolyl-5,6,7,...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175902BDBM175902(US9688684, Compound 99: 8-(4-Isopropoxy-phenyl)-7-...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175901BDBM175901(US9688684, Compound 98: 7-Benzyl-8-(4-butoxy-pheny...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175907BDBM175907(US9688684, Compound 104: 7-(3-Bromo-benzyl)-8-(4-i...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175906BDBM175906(US9688684, Compound 103: 8-(4-Butoxy-phenyl)-7-(3-...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175905BDBM175905(US9688684, Compound 102: 7-Benzyl-8-(4-fluoro-phen...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175904BDBM175904(US9688684, Compound 101: 7-Benzyl-8-(3,5-difluoro-...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175911BDBM175911(US9688684, Compound 108: 7-(3-Bromo-benzyl)-8-(2,5...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175910BDBM175910(US9688684, Compound 107: 7-(3-Bromo-benzyl)-8-(3,5...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175909BDBM175909(US9688684, Compound 106: 8-(4-Chloro-phenyl)-7-thi...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175837BDBM175837(US9688684, Compound 34: 8-(2,5-Difluoro-phenyl)-7-...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175908BDBM175908(US9688684, Compound 105: 7-(3-Methyl-benzyl)-8-phe...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175892BDBM175892(US9688684, Compound 89: 7-Benzyl-8-(3-fluoro-pheny...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175946BDBM175946(US9688684, Compound 143: 7-(3-Chloro-benzyl)-8-(3-...)
Affinity DataIC50: 500nMAssay Description:For the assay 12,500 293T cells (DSMZ no ACC 635) per 384 well are seeded in 30 μl inMEM Eagle medium, supplemented with 10% FBS, 2 mM Glutamax,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175946BDBM175946(US9688684, Compound 143: 7-(3-Chloro-benzyl)-8-(3-...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175891BDBM175891(US9688684, Compound 88: 7-Benzyl-8-(4-isopropoxy-p...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175845BDBM175845(US9688684, Compound 42: 8-(4-Chloro-phenyl)-7-(3-f...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175913BDBM175913(US9688684, Compound 110: 7-(3-Bromo-benzyl)-8-(4-i...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175912BDBM175912(US9688684, Compound 109: {4-[7-(3-Bromo-benzyl)-5,...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175887BDBM175887(US9688684, Compound 84: 8-(4-Fluoro-phenyl)-7-pyri...)
Affinity DataIC50: 500nMAssay Description:For the assay 12,500 293T cells (DSMZ no ACC 635) per 384 well are seeded in 30 μl inMEM Eagle medium, supplemented with 10% FBS, 2 mM Glutamax,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175894BDBM175894(US9688684, Compound 91: 7-(4-Fluoro-benzyl)-8-(3-f...)
Affinity DataIC50: 500nMAssay Description:For the assay 12,500 293T cells (DSMZ no ACC 635) per 384 well are seeded in 30 μl inMEM Eagle medium, supplemented with 10% FBS, 2 mM Glutamax,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175893BDBM175893(US9688684, Compound 90: 7-Benzyl-8-(4-ethyl-phenyl...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175851BDBM175851(US9688684, Compound 48: 7-(3-Isopropyl-1-phenyl-1H...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175893BDBM175893(US9688684, Compound 90: 7-Benzyl-8-(4-ethyl-phenyl...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175896BDBM175896(US9688684, Compound 93: 8-(4-Fluoro-phenyl)-7-(3-m...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175895BDBM175895(US9688684, Compound 92: 7-(3-Bromo-benzyl)-8-m-tol...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175895BDBM175895(US9688684, Compound 92: 7-(3-Bromo-benzyl)-8-m-tol...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175953BDBM175953(US9688684, Compound 150: 7-Benzyl-8-(3-isopropyl-1...)
Affinity DataIC50: 500nMAssay Description:For the assay 12,500 293T cells (DSMZ no ACC 635) per 384 well are seeded in 30 μl inMEM Eagle medium, supplemented with 10% FBS, 2 mM Glutamax,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175855BDBM175855(US9688684, Compound 52: 7-(4-Bromo-benzyl)-8-(3-is...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175864BDBM175864(US9688684, Compound 61: 8-(3-Isopropyl-1-phenyl-1H...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175864BDBM175864(US9688684, Compound 61: 8-(3-Isopropyl-1-phenyl-1H...)
Affinity DataIC50: 500nMAssay Description:For the assay 12,500 293T cells (DSMZ no ACC 635) per 384 well are seeded in 30 μl inMEM Eagle medium, supplemented with 10% FBS, 2 mM Glutamax,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175898BDBM175898(US9688684, Compound 95: 8-(2,3-Dihydro-benzo[1,4]d...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175864BDBM175864(US9688684, Compound 61: 8-(3-Isopropyl-1-phenyl-1H...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175897BDBM175897(US9688684, Compound 94: 7-Benzyl-8-(3-bromo-phenyl...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175896BDBM175896(US9688684, Compound 93: 8-(4-Fluoro-phenyl)-7-(3-m...)
Affinity DataIC50: 500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175900BDBM175900(US9688684, Compound 97: 8-(4-Chloro-phenyl)-7-(3-m...)
Affinity DataIC50: 5.45E+3nMAssay Description:For the assay 12,500 293T cells (DSMZ no ACC 635) per 384 well are seeded in 30 μl inMEM Eagle medium, supplemented with 10% FBS, 2 mM Glutamax,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175820BDBM175820(US9688684, Compound 17: {4-[7-(3-Fluoro-benzyl)-5,...)
Affinity DataIC50: 5.45E+3nMAssay Description:For the assay 12,500 293T cells (DSMZ no ACC 635) per 384 well are seeded in 30 μl inMEM Eagle medium, supplemented with 10% FBS, 2 mM Glutamax,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175899BDBM175899(US9688684, Compound 96: 7-(3-Bromo-benzyl)-8-(4-fl...)
Affinity DataIC50: 5.45E+3nMAssay Description:For the assay 12,500 293T cells (DSMZ no ACC 635) per 384 well are seeded in 30 μl inMEM Eagle medium, supplemented with 10% FBS, 2 mM Glutamax,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 175965BDBM175965(US9688684, Compound 162: 8-(1-Benzyl-3-isopropyl-1...)
Affinity DataIC50: 5.45E+3nMAssay Description:For the assay 12,500 293T cells (DSMZ no ACC 635) per 384 well are seeded in 30 μl inMEM Eagle medium, supplemented with 10% FBS, 2 mM Glutamax,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

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