Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 274
TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261686BDBM261686(US9708295, 27)
Affinity DataIC50: 1.96nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetTyrosine-protein kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261689BDBM261689(US9708295, 30)
Affinity DataKi:  2.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetTyrosine-protein kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261711BDBM261711(US9708295, 53)
Affinity DataKi:  3.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetTyrosine-protein kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261689BDBM261689(US9708295, 30)
Affinity DataKi:  3.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetTyrosine-protein kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261711BDBM261711(US9708295, 53)
Affinity DataKi:  4.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261710BDBM261710(US9708295, 52)
Affinity DataIC50: 6.90nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261695BDBM261695(US9708295, 37)
Affinity DataIC50: 8nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261687BDBM261687(US9708295, 28)
Affinity DataIC50: 9.10nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261689BDBM261689(US9708295, 30)
Affinity DataIC50: 9.80nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261713BDBM261713(US9708295, 55)
Affinity DataIC50: 13.1nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261711BDBM261711(US9708295, 53)
Affinity DataIC50: 13.9nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261689BDBM261689(US9708295, 30)
Affinity DataKi:  18.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261692BDBM261692(US9708295, 34)
Affinity DataIC50: 19nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261688BDBM261688((R)-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-4'-m...)
Affinity DataIC50: 19.2nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261696BDBM261696(US9708295, 38)
Affinity DataIC50: 20nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261690BDBM261690(US9708295, 31)
Affinity DataIC50: 20.8nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261683BDBM261683(US9708295, 24)
Affinity DataIC50: 22.4nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261691BDBM261691(US9708295, 32)
Affinity DataIC50: 27.8nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261700BDBM261700(US9708295, 42)
Affinity DataIC50: 29.4nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261711BDBM261711(US9708295, 53)
Affinity DataKi:  32.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261686BDBM261686(US9708295, 27)
Affinity DataKi:  35.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261681BDBM261681(US9708295, 22)
Affinity DataIC50: 38.1nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261685BDBM261685(US9708295, 26)
Affinity DataIC50: 42nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261704BDBM261704(US9708295, 46)
Affinity DataIC50: 44.8nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261709BDBM261709(5-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5'-m...)
Affinity DataIC50: 46.8nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261684BDBM261684(US9708295, 25)
Affinity DataIC50: 55.1nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261702BDBM261702(US9708295, 44)
Affinity DataIC50: 60.5nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor [G1269S](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261686BDBM261686(US9708295, 27)
Affinity DataKi:  61.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261701BDBM261701(US9708295, 43)
Affinity DataIC50: 64.4nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261682BDBM261682(US9708295, 23)
Affinity DataIC50: 75.7nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261708BDBM261708(US9708295, 50)
Affinity DataIC50: 78nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261680BDBM261680(US9708295, 19)
Affinity DataIC50: 80.2nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261679BDBM261679(US9708295, 18)
Affinity DataIC50: 89.4nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261712BDBM261712(US9708295, 54)
Affinity DataIC50: 90nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261714BDBM261714(US9708295, 56)
Affinity DataIC50: 92.9nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor [G1269S](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261689BDBM261689(US9708295, 30)
Affinity DataKi:  93.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261703BDBM261703(US9708295, 45)
Affinity DataIC50: 105nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261707BDBM261707(US9708295, 49)
Affinity DataIC50: 106nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor [G1269S](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261711BDBM261711(US9708295, 53)
Affinity DataKi:  115nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261697BDBM261697(US9708295, 39)
Affinity DataIC50: 130nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261675BDBM261675(US9708295, 2)
Affinity DataIC50: 136nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261694BDBM261694(US9708295, 36)
Affinity DataIC50: 160nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261705BDBM261705(US9708295, 47)
Affinity DataIC50: 175nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261698BDBM261698(US9708295, 40)
Affinity DataIC50: 227nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261693BDBM261693(US9708295, 35)
Affinity DataIC50: 250nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261706BDBM261706(US9708295, 48)
Affinity DataIC50: 259nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261678BDBM261678(US9708295, 17)
Affinity DataIC50: 396nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261674BDBM261674(US9708295, 1)
Affinity DataIC50: 536nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261699BDBM261699(US9708295, 41)
Affinity DataIC50: 664nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 261677BDBM261677(US9708295, 16)
Affinity DataIC50: 1.00E+3nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

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