Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 395
LigandPNGBDBM264714((R)-1-(6-(4-(4-fluorophenoxy)phenyl)pyridin-2-yl)-...)
Affinity DataIC50: 133nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details
US Patent

LigandPNGBDBM264717((R)-2,3-dihydroxy-1-(6-(4-(4- | US9718780, 4)
Affinity DataIC50: 136nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details
US Patent

LigandPNGBDBM264718((R)-4-(4-(6-(2,3-dihydroxypropanoyl)pyridin-2- | U...)
Affinity DataIC50: 149nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details
US Patent

LigandPNGBDBM264715((R)-4-(4-(6-(2,3-dihydroxypropanoyl)pyridin-2- | U...)
Affinity DataIC50: 365nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details
US Patent

LigandPNGBDBM264716((R)-5-(4-(6-(2,3-dihydroxypropanoyl)pyridin-2- | U...)
Affinity DataIC50: 402nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details
US Patent

LigandPNGBDBM264719(2-(6-(4-(3-cyano-4- | US9718780, 6)
Affinity DataIC50: 722nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details
US Patent