Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 1636
TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333465(N-[4-(3-chloro-4- fluorophenylamino)-7-(2-(6-methy...)
Affinity DataIC50: 0.390nMAssay Description:Assay Procedures:The abbreviations used in the following assay have the following meanings:HEPES: hydroxyethyl piperazine ethanesulfonic acid;Brij-35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333467(N-[4-(3-chloro-4- fluorophenylamino)-7-(2-(7-methy...)
Affinity DataIC50: 0.560nMAssay Description:Assay Procedures:The abbreviations used in the following assay have the following meanings:HEPES: hydroxyethyl piperazine ethanesulfonic acid;Brij-35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333448(N-[4-(3-chloro-4- fluorophenylamino)-7-(2- ((1R,5S...)
Affinity DataIC50: 0.660nMAssay Description:Assay Procedures:The abbreviations used in the following assay have the following meanings:HEPES: hydroxyethyl piperazine ethanesulfonic acid;Brij-35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333449(N-[4-(3-chloro-4- fluorophenylamino)-7-(2-(3-methy...)
Affinity DataIC50: 0.800nMAssay Description:Assay Procedures:The abbreviations used in the following assay have the following meanings:HEPES: hydroxyethyl piperazine ethanesulfonic acid;Brij-35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333447(N-[4-(3-chloro-4- fluorophenylamino)-7-(8-methyl-1...)
Affinity DataIC50: 0.930nMAssay Description:Assay Procedures:The abbreviations used in the following assay have the following meanings:HEPES: hydroxyethyl piperazine ethanesulfonic acid;Brij-35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333466(N-[4-(3-chloro-4- fluorophenylamino)-7-((7-methyl-...)
Affinity DataIC50: 1nMAssay Description:Assay Procedures:The abbreviations used in the following assay have the following meanings:HEPES: hydroxyethyl piperazine ethanesulfonic acid;Brij-35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333446(N-[4-(3-chloro-4- fluorophenylamino)-7-((8-methyl-...)
Affinity DataIC50: 1nMAssay Description:Assay Procedures:The abbreviations used in the following assay have the following meanings:HEPES: hydroxyethyl piperazine ethanesulfonic acid;Brij-35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-4(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333465(N-[4-(3-chloro-4- fluorophenylamino)-7-(2-(6-methy...)
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-4(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333446(N-[4-(3-chloro-4- fluorophenylamino)-7-((8-methyl-...)
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 1.60nMAssay Description:Assay Procedures:The abbreviations used in the following assay have the following meanings:HEPES: hydroxyethyl piperazine ethanesulfonic acid;Brij-35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333447(N-[4-(3-chloro-4- fluorophenylamino)-7-(8-methyl-1...)
Affinity DataIC50: 1.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-4(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333466(N-[4-(3-chloro-4- fluorophenylamino)-7-((7-methyl-...)
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333465(N-[4-(3-chloro-4- fluorophenylamino)-7-(2-(6-methy...)
Affinity DataIC50: 2.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333467(N-[4-(3-chloro-4- fluorophenylamino)-7-(2-(7-methy...)
Affinity DataIC50: 3.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-4(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333448(N-[4-(3-chloro-4- fluorophenylamino)-7-(2- ((1R,5S...)
Affinity DataIC50: 3.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-4(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333467(N-[4-(3-chloro-4- fluorophenylamino)-7-(2-(7-methy...)
Affinity DataIC50: 3.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333447(N-[4-(3-chloro-4- fluorophenylamino)-7-(8-methyl-1...)
Affinity DataIC50: 4.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333466(N-[4-(3-chloro-4- fluorophenylamino)-7-((7-methyl-...)
Affinity DataIC50: 6.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333448(N-[4-(3-chloro-4- fluorophenylamino)-7-(2- ((1R,5S...)
Affinity DataIC50: 6.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333446(N-[4-(3-chloro-4- fluorophenylamino)-7-((8-methyl-...)
Affinity DataIC50: 7.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM4779(cid_156414 | PD0183805 | CHEMBL545315 | CHEMBL3196...)
Affinity DataIC50: 7.60nMAssay Description:Assay Procedures:The abbreviations used in the following assay have the following meanings:HEPES: hydroxyethyl piperazine ethanesulfonic acid;Brij-35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-4(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 7.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-4(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM4779(cid_156414 | PD0183805 | CHEMBL545315 | CHEMBL3196...)
Affinity DataIC50: 7.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM4779(cid_156414 | PD0183805 | CHEMBL545315 | CHEMBL3196...)
Affinity DataIC50: 7.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 7.60nMAssay Description:Assay Procedures:The abbreviations used in the following assay have the following meanings:HEPES: hydroxyethyl piperazine ethanesulfonic acid;Brij-35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 7.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-4(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 7.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 7.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 7.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 7.60nMAssay Description:Assay Procedures:The abbreviations used in the following assay have the following meanings:HEPES: hydroxyethyl piperazine ethanesulfonic acid;Brij-35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-4(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333449(N-[4-(3-chloro-4- fluorophenylamino)-7-(2-(3-methy...)
Affinity DataIC50: 8.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM333449(N-[4-(3-chloro-4- fluorophenylamino)-7-(2-(3-methy...)
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 318nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent