Compile Data Set for Download or QSAR
Report error Found 194 Enz. Inhib. hit(s) with all data for entry = 1647
TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334348BDBM334348(1-(4-((2-((3-(2,5,8,11,14,17,20-Heptaoxadocosan-22...)
Affinity DataIC50: 3nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
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Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334378BDBM334378(1-(3-(tert-Butyl)-1-(P-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 4nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 334346BDBM334346(1-(4-((2-((3-(2,5,8,11,14-Pentaoxahexadecan-16-ylo...)
Affinity DataIC50: 4nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334335BDBM334335(1-(4-((2-((3-(2-(2-(2-Hydroxyethoxy)ethoxy)ethoxy)...)
Affinity DataIC50: 5nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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LigandChemical structure of BindingDB Monomer ID 334378BDBM334378(1-(3-(tert-Butyl)-1-(P-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 6nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334345BDBM334345(1-(4-((2-((3-(2,5,8,11-Tetraoxatridecan-13-yloxy)-...)
Affinity DataIC50: 6nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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LigandChemical structure of BindingDB Monomer ID 334348BDBM334348(1-(4-((2-((3-(2,5,8,11,14,17,20-Heptaoxadocosan-22...)
Affinity DataIC50: 7nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 334373BDBM334373(1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 7nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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LigandChemical structure of BindingDB Monomer ID 334336BDBM334336(1-(4-((2-((3-(2-(2-(2-Hydroxyethoxy)ethoxy)ethoxy)...)
Affinity DataIC50: 8nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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LigandChemical structure of BindingDB Monomer ID 334373BDBM334373(1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 8nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 334318BDBM334318(S,S-Dimethyl-N-(4-((4-((4-(3-(3-(tert-butyl)-1-(6-...)
Affinity DataIC50: 8nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 334336BDBM334336(1-(4-((2-((3-(2-(2-(2-Hydroxyethoxy)ethoxy)ethoxy)...)
Affinity DataIC50: 8nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 334329BDBM334329(1-(3-Isopropyl-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(4-(...)
Affinity DataIC50: 10nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 334354BDBM334354(1-(3-(tert-Butyl)-1-(6-methoxypyridin-3-yl)-1H-pyr...)
Affinity DataIC50: 10nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 334367BDBM334367(1-(4-((2-((3-(2,5,8,11,14,17,20-Heptaoxadocosan-22...)
Affinity DataIC50: 10nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334360BDBM334360(1-(3-(tert-Butyl)-1-(4-methoxyphenyl)-1H-pyrazol-5...)
Affinity DataIC50: 10nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetMitogen-activated protein kinase 12(Human)
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LigandChemical structure of BindingDB Monomer ID 334348BDBM334348(1-(4-((2-((3-(2,5,8,11,14,17,20-Heptaoxadocosan-22...)
Affinity DataIC50: 11nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 334374BDBM334374(1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 11nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334353BDBM334353(1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 11nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 334361BDBM334361(1-(3-(tert-Butyl)-1-(P-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 12nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334346BDBM334346(1-(4-((2-((3-(2,5,8,11,14-Pentaoxahexadecan-16-ylo...)
Affinity DataIC50: 12nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334379BDBM334379(1-(3-(tert-Butyl)-1-(4-(dimethylamino)phenyl)-1H-p...)
Affinity DataIC50: 13nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334385BDBM334385(1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 14nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334318BDBM334318(S,S-Dimethyl-N-(4-((4-((4-(3-(3-(tert-butyl)-1-(6-...)
Affinity DataIC50: 15nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334361BDBM334361(1-(3-(tert-Butyl)-1-(P-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 15nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334351BDBM334351(1-(2,3-Dichloro-4-((2-((3-methoxy-5-(2-(2-(2-metho...)
Affinity DataIC50: 15nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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LigandChemical structure of BindingDB Monomer ID 334345BDBM334345(1-(4-((2-((3-(2,5,8,11-Tetraoxatridecan-13-yloxy)-...)
Affinity DataIC50: 16nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334379BDBM334379(1-(3-(tert-Butyl)-1-(4-(dimethylamino)phenyl)-1H-p...)
Affinity DataIC50: 16nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 334319BDBM334319(3-(4-((4-(3-(3-(tert-Butyl)-1-(6-methoxypyridin-3-...)
Affinity DataIC50: 16nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334329BDBM334329(1-(3-Isopropyl-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(4-(...)
Affinity DataIC50: 17nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 334376BDBM334376(1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 17nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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LigandChemical structure of BindingDB Monomer ID 334367BDBM334367(1-(4-((2-((3-(2,5,8,11,14,17,20-Heptaoxadocosan-22...)
Affinity DataIC50: 18nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 334387BDBM334387(1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 19nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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LigandChemical structure of BindingDB Monomer ID 334335BDBM334335(1-(4-((2-((3-(2-(2-(2-Hydroxyethoxy)ethoxy)ethoxy)...)
Affinity DataIC50: 20nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334365BDBM334365(1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 20nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 334327BDBM334327(3-(4-((4-(3-(3-Isopropyl-1-(p-tolyl)-1H-pyrazol-5-...)
Affinity DataIC50: 20nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 334364BDBM334364(1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 22nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334360BDBM334360(1-(3-(tert-Butyl)-1-(4-methoxyphenyl)-1H-pyrazol-5...)
Affinity DataIC50: 23nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334365BDBM334365(1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 23nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334369BDBM334369(1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 23nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334371BDBM334371(1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 23nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334387BDBM334387(1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 23nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334354BDBM334354(1-(3-(tert-Butyl)-1-(6-methoxypyridin-3-yl)-1H-pyr...)
Affinity DataIC50: 25nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetMitogen-activated protein kinase 12(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334325BDBM334325(1-(3-Isopropyl-1-(P-tolyl)-1H-pyrazol-5-yl)-3-(4-(...)
Affinity DataIC50: 26nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetMitogen-activated protein kinase 12(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334336BDBM334336(1-(4-((2-((3-(2-(2-(2-Hydroxyethoxy)ethoxy)ethoxy)...)
Affinity DataIC50: 26nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334385BDBM334385(1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 27nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334334BDBM334334(1-(4-((2-((3-(Cyclopropylsulfonyl)-5-methoxyphenyl...)
Affinity DataIC50: 27nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334372BDBM334372(1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 28nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334317BDBM334317(1-(3-(tert-Butyl)-1-(6-methoxypyridin-3-yl)-1H-pyr...)
Affinity DataIC50: 28nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 334358BDBM334358(1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50: 28nMAssay Description:c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

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