Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 1689
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335705(5-(Ethyl(tetrahydro-2H-pyran-4- yl)amino)-4-methyl...)
Affinity DataEC50: <50nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335723(2,2-Dimethyl-N-((1-methyl-3- oxo-2,3-dihydroisoqui...)
Affinity DataEC50: <5.00E+3nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335707(N-((6,7-Dimethoxy-1-methyl-3- oxo-2,3-dihydroisoqu...)
Affinity DataEC50: <5.00E+3nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335708(5-(Ethyl(tetrahydro-2H-pyran-4- yl)amino)-N-((6-me...)
Affinity DataEC50: <5.00E+3nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335709(5-(Ethyl(tetrahydro-2H-pyran-4- yl)amino)-N-((5-fl...)
Affinity DataEC50: <5.00E+3nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335711(5-(Ethyl(tetrahydro-2H-pyran-4- yl)amino)-N-((5-fl...)
Affinity DataEC50: <50nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335712(5-(Ethyl(tetrahydro-2H-pyran-4- yl)amino)-4-methyl...)
Affinity DataEC50: <500nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335713(4'-((1,1-Dioxidothiomorpholino) methyl)-5-(ethyl(t...)
Affinity DataEC50: <500nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335714(US9738630, Example 9 | tert-Butyl 4-(5-(1-(sec-but...)
Affinity DataEC50: <5.00E+3nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335715(1-(sec-Butyl)-3-methyl-N-((1- methyl-3-oxo-2,3- di...)
Affinity DataEC50: <500nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335716(N-((6,8-Difluoro-1-methyl-3-oxo- 2,3-dihydroisoqui...)
Affinity DataEC50: <5.00E+3nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335717(5-(Ethyl(tetrahydro-2H-pyran-4- yl)amino)-N-((8-fl...)
Affinity DataEC50: <5.00E+3nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335706(5-(Ethyl(tetrahydro-2H-pyran-4- yl)amino)-N-((7-fl...)
Affinity DataEC50: <500nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335719(5-(Ethyl(tetrahydro-2H-pyran-4- yl)amino)-N-((1-et...)
Affinity DataEC50: <500nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335720(5-(Ethyl(tetrahydro-2H-pyran-4- yl)amino)-N-((1-et...)
Affinity DataEC50: <50nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335722(N-((1,7-Dimethyl-3-oxo-2,3- dihydroisoquinolin-4-y...)
Affinity DataEC50: <50nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335706(5-(Ethyl(tetrahydro-2H-pyran-4- yl)amino)-N-((7-fl...)
Affinity DataEC50: <50nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent