Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 1690
TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141376BDBM141376(US8916600, 10 | US9738632, Example 10)
Affinity DataIC50: 0.647nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141385BDBM141385(US8916600, 19 | US9738632, Example 19)
Affinity DataIC50: 0.663nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141378BDBM141378(US8916600, 12 | US9738632, Example 12)
Affinity DataIC50: 0.767nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141373BDBM141373(US8916600, 7 | US9738632, Example 8)
Affinity DataIC50: 0.796nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141379BDBM141379(US8916600, 13 | US9738632, Example 13)
Affinity DataIC50: 0.817nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141372BDBM141372(US8916600, 6 | US9738632, Example 6)
Affinity DataIC50: 0.913nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141383BDBM141383(US8916600, 17 | US9738632, Example 17)
Affinity DataIC50: 0.996nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141371BDBM141371(US8916600, 5 | US9738632, Example 5)
Affinity DataIC50: 1.08nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141375BDBM141375(US8916600, 9 | US9738632, Example 9)
Affinity DataIC50: 1.09nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141373BDBM141373(US8916600, 7 | US9738632, Example 8)
Affinity DataIC50: 1.30nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141367BDBM141367(US8916600, 4 | US8916600, 1 | US9738632, Example 1)
Affinity DataIC50: 1.32nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141368BDBM141368(US8916600, 3 | US8916600, 2 | US9738632, Example 2)
Affinity DataIC50: 1.36nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 335727BDBM335727(US9738632, Example 4)
Affinity DataIC50: 1.40nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 335726BDBM335726(US9738632, Example 3)
Affinity DataIC50: 1.60nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141380BDBM141380(US8916600, 14 | US9738632, Example 14)
Affinity DataIC50: 1.75nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141386BDBM141386(US8916600, 20 | US9738632, Example 20)
Affinity DataIC50: 1.96nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141377BDBM141377(US8916600, 11 | US9738632, Example 11)
Affinity DataIC50: 2.15nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141384BDBM141384(US8916600, 18 | US9738632, Example 18)
Affinity DataIC50: 3.44nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141381BDBM141381(US8916600, 16 | US8916600, 15 | US9738632, Example...)
Affinity DataIC50: 3.64nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 141381BDBM141381(US8916600, 16 | US8916600, 15 | US9738632, Example...)
Affinity DataIC50: 4.27nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent