Compile Data Set for Download or QSAR
Report error Found 370 Enz. Inhib. hit(s) with all data for entry = 1771
TargetFibroblast growth factor receptor 2(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339807BDBM339807(US9757364, Compound 11)
Affinity DataIC50: 0.126nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339838BDBM339838(US9757364, Compound 39)
Affinity DataIC50: 0.355nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339871BDBM339871(US9757364, Compound 55)
Affinity DataIC50: 0.417nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339823BDBM339823(US9757364, Compound 16)
Affinity DataIC50: 0.447nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339803BDBM339803(US9757364, Compound 10)
Affinity DataIC50: 0.501nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339807BDBM339807(US9757364, Compound 11)
Affinity DataIC50: 0.501nMAssay Description:In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339869BDBM339869(US9757364, Compound 57)
Affinity DataIC50: 0.550nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339822BDBM339822(US9757364, Compound 15)
Affinity DataIC50: 0.550nMAssay Description:In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339823BDBM339823(US9757364, Compound 16)
Affinity DataIC50: 0.575nMAssay Description:In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339838BDBM339838(US9757364, Compound 39)
Affinity DataIC50: 0.603nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339803BDBM339803(US9757364, Compound 10)
Affinity DataIC50: 0.631nMAssay Description:In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339804BDBM339804(US9757364, Compound 2)
Affinity DataIC50: 0.631nMAssay Description:In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339825BDBM339825(US9757364, Compound 31)
Affinity DataIC50: 0.676nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339848BDBM339848(US9757364, Compound 47)
Affinity DataIC50: 0.692nMAssay Description:In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339822BDBM339822(US9757364, Compound 15)
Affinity DataIC50: 0.724nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339838BDBM339838(US9757364, Compound 39)
Affinity DataIC50: 0.724nMAssay Description:In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339822BDBM339822(US9757364, Compound 15)
Affinity DataIC50: 0.759nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339807BDBM339807(US9757364, Compound 11)
Affinity DataIC50: 0.794nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339866BDBM339866(US9757364, Compound 58)
Affinity DataIC50: 0.851nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339868BDBM339868(US9757364, Compound 62)
Affinity DataIC50: 0.851nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339846BDBM339846(US9757364, Compound 46)
Affinity DataIC50: 0.912nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339838BDBM339838(US9757364, Compound 39)
Affinity DataIC50: 0.912nMAssay Description:In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339850BDBM339850(US9757364, Compound 49)
Affinity DataIC50: 0.933nMAssay Description:In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339843BDBM339843(US9757364, Compound 42 | US9757364, Compound 44)
Affinity DataIC50: 0.955nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339843BDBM339843(US9757364, Compound 42 | US9757364, Compound 44)
Affinity DataIC50: 0.977nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339812BDBM339812(US9757364, Compound 26)
Affinity DataIC50: 0.977nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339843BDBM339843(US9757364, Compound 42 | US9757364, Compound 44)
Affinity DataIC50: 1nMAssay Description:In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339803BDBM339803(US9757364, Compound 10)
Affinity DataIC50: 1nMAssay Description:In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339798BDBM339798(US9757364, Compound 1)
Affinity DataIC50: 1nMAssay Description:In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339805BDBM339805(US9757364, Compound 7)
Affinity DataIC50: 1nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339823BDBM339823(US9757364, Compound 16)
Affinity DataIC50: 1.02nMAssay Description:In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339837BDBM339837(US9757364, Compound 43 | US9757364, Compound 40)
Affinity DataIC50: 1.07nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339849BDBM339849(US9757364, Compound 48)
Affinity DataIC50: 1.10nMAssay Description:In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339829BDBM339829(US9757364, Compound 29)
Affinity DataIC50: 1.10nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339849BDBM339849(US9757364, Compound 48)
Affinity DataIC50: 1.12nMAssay Description:In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339847BDBM339847(US9757364, Compound 45)
Affinity DataIC50: 1.15nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339811BDBM339811(US9757364, Compound 65)
Affinity DataIC50: 1.15nMAssay Description:In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339871BDBM339871(US9757364, Compound 55)
Affinity DataIC50: 1.17nMAssay Description:In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339869BDBM339869(US9757364, Compound 57)
Affinity DataIC50: 1.20nMAssay Description:In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339843BDBM339843(US9757364, Compound 42 | US9757364, Compound 44)
Affinity DataIC50: 1.20nMAssay Description:In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339869BDBM339869(US9757364, Compound 57)
Affinity DataIC50: 1.20nMAssay Description:In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339828BDBM339828(US9757364, Compound 30)
Affinity DataIC50: 1.20nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339804BDBM339804(US9757364, Compound 2)
Affinity DataIC50: 1.26nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339801BDBM339801(US9757364, Compound 4)
Affinity DataIC50: 1.26nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339819BDBM339819(US9757364, Compound 13)
Affinity DataIC50: 1.29nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339823BDBM339823(US9757364, Compound 16)
Affinity DataIC50: 1.29nMAssay Description:In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339836BDBM339836(US9757364, Compound 34)
Affinity DataIC50: 1.29nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339811BDBM339811(US9757364, Compound 65)
Affinity DataIC50: 1.29nMAssay Description:In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339849BDBM339849(US9757364, Compound 48)
Affinity DataIC50: 1.35nMAssay Description:In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 339840BDBM339840(US9757364, Compound 41 | US9757364, Compound 37)
Affinity DataIC50: 1.35nMAssay Description:In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

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