Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 1857
TargetEpidermal growth factor receptor [L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 0.458nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 0.508nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM50391089(CHEMBL2087361 | Icotinib | Conmana | BPI-2009 | Lc...)
Affinity DataIC50: 1.23nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM50391089(CHEMBL2087361 | Icotinib | Conmana | BPI-2009 | Lc...)
Affinity DataIC50: 2.02nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270538(US10059688, Example 4 | US9783524, Example 4)
Affinity DataIC50: 4.08nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270544(2-(2-(5-chloro-2-(4-(4- (dimethylamino)piperidin- ...)
Affinity DataIC50: 4.92nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270544(2-(2-(5-chloro-2-(4-(4- (dimethylamino)piperidin- ...)
Affinity DataIC50: 5.13nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270538(US10059688, Example 4 | US9783524, Example 4)
Affinity DataIC50: 7.52nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270543(US10059688, Example 115 | US9783524, Example 115)
Affinity DataIC50: 8.62nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514) 1. 2.5 uL-4x Test Compound or 100 nL 100x plus 2.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM344704(Compound 74 | US9783524, Example 74)
Affinity DataIC50: 9.33nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514) 1. 2.5 uL-4x Test Compound or 100 nL 100x plus 2.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270544(2-(2-(5-chloro-2-(4-(4- (dimethylamino)piperidin- ...)
Affinity DataIC50: 10.8nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514) 1. 2.5 uL-4x Test Compound or 100 nL 100x plus 2.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270543(US10059688, Example 115 | US9783524, Example 115)
Affinity DataIC50: 11.7nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270539(2-(2-(5-chloro-2-(3-methoxy- 4-(4-methylpiperazin-...)
Affinity DataIC50: 12.2nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514) 1. 2.5 uL-4x Test Compound or 100 nL 100x plus 2.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 13.7nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor [T790M,L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270542(2-(2-(2-(4-acryloyl-3,4- dihydro-2H-benzo[b][1,4] ...)
Affinity DataIC50: 14.7nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270542(2-(2-(2-(4-acryloyl-3,4- dihydro-2H-benzo[b][1,4] ...)
Affinity DataIC50: 15.1nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514) 1. 2.5 uL-4x Test Compound or 100 nL 100x plus 2.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270540(N-(3-(5-chloro-4-(2-(2- (dimethylamino)-2-oxoacety...)
Affinity DataIC50: 15.4nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM344704(Compound 74 | US9783524, Example 74)
Affinity DataIC50: 15.5nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM344704(Compound 74 | US9783524, Example 74)
Affinity DataIC50: 15.8nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 16.6nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270540(N-(3-(5-chloro-4-(2-(2- (dimethylamino)-2-oxoacety...)
Affinity DataIC50: 17.3nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514) 1. 2.5 uL-4x Test Compound or 100 nL 100x plus 2.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270543(US10059688, Example 115 | US9783524, Example 115)
Affinity DataIC50: 18.7nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270540(N-(3-(5-chloro-4-(2-(2- (dimethylamino)-2-oxoacety...)
Affinity DataIC50: 18.9nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270542(2-(2-(2-(4-acryloyl-3,4- dihydro-2H-benzo[b][1,4] ...)
Affinity DataIC50: 21.3nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270539(2-(2-(5-chloro-2-(3-methoxy- 4-(4-methylpiperazin-...)
Affinity DataIC50: 22.8nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270538(US10059688, Example 4 | US9783524, Example 4)
Affinity DataIC50: 27.9nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514) 1. 2.5 uL-4x Test Compound or 100 nL 100x plus 2.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270539(2-(2-(5-chloro-2-(3-methoxy- 4-(4-methylpiperazin-...)
Affinity DataIC50: 38.2nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270538(US10059688, Example 4 | US9783524, Example 4)
Affinity DataIC50: 44.3nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270538(US10059688, Example 4 | US9783524, Example 4)
Affinity DataIC50: 45.1nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270544(2-(2-(5-chloro-2-(4-(4- (dimethylamino)piperidin- ...)
Affinity DataIC50: 77.6nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 101nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor [L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 108nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 145nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514) 1. 2.5 uL-4x Test Compound or 100 nL 100x plus 2.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270544(2-(2-(5-chloro-2-(4-(4- (dimethylamino)piperidin- ...)
Affinity DataIC50: 158nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 179nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor [L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270542(2-(2-(2-(4-acryloyl-3,4- dihydro-2H-benzo[b][1,4] ...)
Affinity DataIC50: 225nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270540(N-(3-(5-chloro-4-(2-(2- (dimethylamino)-2-oxoacety...)
Affinity DataIC50: 273nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270542(2-(2-(2-(4-acryloyl-3,4- dihydro-2H-benzo[b][1,4] ...)
Affinity DataIC50: 354nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270543(US10059688, Example 115 | US9783524, Example 115)
Affinity DataIC50: 397nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 412nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor [L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM344704(Compound 74 | US9783524, Example 74)
Affinity DataIC50: 422nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270540(N-(3-(5-chloro-4-(2-(2- (dimethylamino)-2-oxoacety...)
Affinity DataIC50: 500nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM344704(Compound 74 | US9783524, Example 74)
Affinity DataIC50: 513nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270543(US10059688, Example 115 | US9783524, Example 115)
Affinity DataIC50: 547nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270539(2-(2-(5-chloro-2-(3-methoxy- 4-(4-methylpiperazin-...)
Affinity DataIC50: 756nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM270539(2-(2-(5-chloro-2-(3-methoxy- 4-(4-methylpiperazin-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM50391089(CHEMBL2087361 | Icotinib | Conmana | BPI-2009 | Lc...)
Affinity DataIC50: 1.00E+3nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM50391089(CHEMBL2087361 | Icotinib | Conmana | BPI-2009 | Lc...)
Affinity DataIC50: 1.00E+3nMAssay Description:Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent