Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 2027
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350906(US9796687, Compound 28 | 3-Phenyl-2-(2-naphthylmet...)
Affinity DataIC50: 90nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
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US Patent
LigandPNGBDBM350888(US9796687, Compound 5 | 3-Phenyl-2-neopentylthio-4...)
Affinity DataIC50: 100nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350903(US9796687, Compound 26 | 3-(2-Methylphenyl)-2-(3-p...)
Affinity DataIC50: 120nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
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US Patent
LigandPNGBDBM350886(US9796687, Compound 1 | 2-Cyclohexylmethylthio-3-p...)
Affinity DataIC50: 200nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350902(US9796687, Compound 25 | 8-Chloro-2-(3-pyridylmeth...)
Affinity DataIC50: 540nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350899(US9796687, Compound 21 | 2-Benzylthio-3-phenyl-4-o...)
Affinity DataIC50: 600nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350901(US9796687, Compound 24 | 3-Phenyl-2-(3-pyridylmeth...)
Affinity DataIC50: 700nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350900(US9796687, Compound 23 | 3-Phenyl-2-(2-pyridylmeth...)
Affinity DataIC50: 800nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350890(US9796687, Compound 11 | 8-Chloro-3-phenyl-2-neope...)
Affinity DataIC50: 1.20E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350891(US9796687, Compound 13 | 3-(2-Methylphenyl)-2-neop...)
Affinity DataIC50: 1.85E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350887(US9796687, Compound 2 | 3-(2-Bromophenyl)-2-cycloh...)
Affinity DataIC50: 2.11E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350898(US9796687, Compound 18 | 8-Chloro-2-ethylthio-3-(2...)
Affinity DataIC50: 2.44E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350904(US9796687, Compound 27 | 3-Phenyl-2-(4-pyridylmeth...)
Affinity DataIC50: 2.60E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350893(US9796687, Compound 15 | 2-Cyclopropylmethylthio-3...)
Affinity DataIC50: 4.56E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350894(US9796687, Compound 16 | 2-Ethylthio-3-phenyl-4-ox...)
Affinity DataIC50: 6.90E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350895(US9796687, Compound 17 | 2-Ethylthio-3-(2,6-difluo...)
Affinity DataIC50: 6.99E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350889(US9796687, Compound 6 | 3-(2,6-Difluorophenyl)-8-m...)
Affinity DataIC50: 8.67E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM350892(US9796687, Compound 14 | 3-(2-Bromophenyl)-2-cyclo...)
Affinity DataIC50: 9.44E+3nMAssay Description:Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent