Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 2056
TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351897BDBM351897((S)-5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)propan-2-y...)
Affinity DataKi:  0.660nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351895BDBM351895((S)-5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)propan-2-y...)
Affinity DataKi:  0.670nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351893BDBM351893((S)-2-(9-Fluoro-2-(4-(1-methyl-1H-tetrazol-5-yl)ph...)
Affinity DataKi:  0.760nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351896BDBM351896((S)-5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)propan-2-y...)
Affinity DataKi:  0.820nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351905BDBM351905((S)-5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)propan-2-y...)
Affinity DataKi:  1.40nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351892BDBM351892(4-(1-Methyl-1H-tetrazol-5-yl)phenylboronic acid | ...)
Affinity DataKi:  1.40nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351908BDBM351908((S)-N-(4-(5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)prop...)
Affinity DataKi:  1.76nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351909BDBM351909((S)-1-(4-(5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)prop...)
Affinity DataKi:  1.90nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351916BDBM351916((S)-5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)propan-2-y...)
Affinity DataKi:  1.94nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351894BDBM351894(6-(Morpholine-4-carbonyl)pyridin-3-ylboronic acid ...)
Affinity DataKi:  2.10nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351891BDBM351891((S)-2-(9-Fluoro-2-(4-(morpholine-4-carbonyl)phenyl...)
Affinity DataKi:  2.34nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351888BDBM351888((S)-5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)propan-2-y...)
Affinity DataKi:  2.35nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351898BDBM351898((S)-5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)propan-2-y...)
Affinity DataKi:  2.36nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351889BDBM351889((S)-5-(2-(3H-Imidazo[4,5-b]pyridin-2-yl)propan-2-y...)
Affinity DataKi:  2.63nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351910BDBM351910((S)-5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)propan-2-y...)
Affinity DataKi:  2.78nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351890BDBM351890((S)-5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)propan-2-y...)
Affinity DataKi:  2.89nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351907BDBM351907((S)-4-(5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)propan-...)
Affinity DataKi:  2.91nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351887BDBM351887((S)-2-(2-Chloro-9-fluoro-5H-chromeno[2,3-b]pyridin...)
Affinity DataKi:  3.28nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351906BDBM351906((S)-5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)propan-2-y...)
Affinity DataKi:  3.92nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351914BDBM351914((S)-5-(5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)propan-...)
Affinity DataKi:  5.43nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351912BDBM351912((S)-2-(5-(5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)prop...)
Affinity DataKi:  9.30nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351901BDBM351901((S)-(4-(5-(2-(9H-Purin-8-yl)propan-2-yl)-9-fluoro-...)
Affinity DataKi:  12.4nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351903BDBM351903((S)-5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)propan-2-y...)
Affinity DataKi:  16nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351899BDBM351899((S)-(4-(5-(2-(1H-Benzo[d]imidazol-2-yl)propan-2-yl...)
Affinity DataKi:  16.1nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351913BDBM351913((S)-5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)propan-2-y...)
Affinity DataKi:  28.6nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351915BDBM351915((S)-(5-(5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)propan...)
Affinity DataKi:  30.3nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351886BDBM351886((S)-2-(2-Chloro-9-fluoro-5H-chromeno[2,3-b]pyridin...)
Affinity DataKi:  57nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351902BDBM351902((S)-5-(2-(9H-Purin-8-yl)propan-2-yl)-9-fluoro-2-(4...)
Affinity DataKi:  65.8nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351904BDBM351904((S)-N-(4-(5-(2-(1H-Imidazo[4,5-b]pyrazin-2-yl)prop...)
Affinity DataKi:  70.5nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351900BDBM351900((S)-(4-(5-(2-(3H-Imidazo[4,5-b]pyridin-2-yl)propan...)
Affinity DataKi:  121nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 351911BDBM351911((S)-Methyl 5-(5-(2-(1H-imidazo[4,5-b]pyrazin-2-yl)...)
Affinity DataKi:  144nMAssay Description:In order to measure the binding of compounds on the glucocorticoid receptor a commercially available kit was used (Glucocorticoid receptor competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent