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Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 2104
TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352433(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352434(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352435(N-((1S*,4S*,7R*)-2-(3-Amino-5-methylisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352437(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352438(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352439(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352440(N-((1S*,4S*,7R*)-2-(3-Amino-5-methylisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352441(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352442(N-((1S*,4S*,7R*)-2-(3-Amino-5-methylisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352443(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352444(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352445(4-([1,2,4]Triazolo[4,3-a]pyridin-6-yl)-N-((1S*,4S*...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352446(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352447(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352448(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352449(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352450(N-((1S*,4S*,7R*)-2-(3-Amino-5-cyanoisoxazolo[5,4-c...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352451(N-((1S*,4S*,7R*)-2-(3-Amino-5-methylisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352452(N-((1S*,4S*,7R*)-2-(3-Amino-5-methylisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352453(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352454(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352422(N-((1S*,4S*, 7R*)-2-(3-Aminobenzo[d]isoxazol-7-yl)...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352423(N-((1S*,4S*,7R*)-2-(3-Aminoisoxazolo[5,4-c]pyridin...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352424(N-((1S*,4S*,7R*)-2-(3-Amino-5-methylbenzo[d]isoxaz...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352425(N-((1S*,4S*,7R*)-2-(3-Amino-5-chlorobenzo[d]isoxaz...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352427(N-((1S*,4S*,7R*)-2-(3-Amino-4-chlorobenzo[d]isoxaz...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352428(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352429(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352431(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352432(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50:  550nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352429(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50:  550nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352435(N-((1S*,4S*,7R*)-2-(3-Amino-5-methylisoxazolo[5,4-...)
Affinity DataIC50:  550nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent