Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 2448
TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366072BDBM366072(5-[4-[5-(2-Methoxybenzyl)-1H-tetrazol-1-yl]phenyl]...)
Affinity DataIC50: 25nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366073BDBM366073(5-[4-[5-(2-Hydroxybenzyl)-1H-tetrazol-1-yl]phenyl]...)
Affinity DataIC50: 37nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366069BDBM366069(US9873683, Example 79)
Affinity DataIC50: 39nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366075BDBM366075(5-[4-(5-Phenethyl-1H-tetrazol-1-yl)phenyl]-1H-naph...)
Affinity DataIC50: 44nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 365870BDBM365870(US9873683, Example 31)
Affinity DataIC50: 51nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366062BDBM366062(US9873683, Example 67)
Affinity DataIC50: 53nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366049BDBM366049(US9873683, Example 43)
Affinity DataIC50: 53nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366057BDBM366057(US9873683, Example 61)
Affinity DataIC50: 74nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366078BDBM366078(5-[6-[5-(2-Hydroxybenzyl)-1H-tetrazol-1-yl]pyridin...)
Affinity DataIC50: 77nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366077BDBM366077(5-[4-(2-Phenethyl-1H-imidazol-1-yl)phenyl]-1H-naph...)
Affinity DataIC50: 78nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 365827BDBM365827(US9873683, Example 27)
Affinity DataIC50: 78nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 365950BDBM365950(US9873683, Example 37)
Affinity DataIC50: 79nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 365816BDBM365816(US9873683, Example 25)
Affinity DataIC50: 82nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366071BDBM366071(US9873683, Example 83)
Affinity DataIC50: 87nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366058BDBM366058(US9873683, Example 62)
Affinity DataIC50: 88nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 365756BDBM365756(US9873683, Example 22)
Affinity DataIC50: 91nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366048BDBM366048(US9873683, Example 42)
Affinity DataIC50: 92nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366050BDBM366050(US9873683, Example 47)
Affinity DataIC50: 94nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366060BDBM366060(US9873683, Example 65)
Affinity DataIC50: 130nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366056BDBM366056(US9873683, Example 57)
Affinity DataIC50: 130nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 365944BDBM365944(US9873683, Example 32)
Affinity DataIC50: 180nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366054BDBM366054(US9873683, Example 54)
Affinity DataIC50: 190nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 365840BDBM365840(US9873683, Example 30)
Affinity DataIC50: 270nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 365785BDBM365785(US9873683, Example 23)
Affinity DataIC50: 300nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366067BDBM366067(US9873683, Example 73)
Affinity DataIC50: 320nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366076BDBM366076(5-[4-[5-(2-Methoxybenzyl)-1H-tetrazol-1-yl]phenyl]...)
Affinity DataIC50: 320nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366055BDBM366055(US9873683, Example 55)
Affinity DataIC50: 340nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366074BDBM366074(5-[4-[5-[2-(Pyridin-3-yl)ethyl]-1H-tetrazol-1-yl]p...)
Affinity DataIC50: 380nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366059BDBM366059(US9873683, Example 64)
Affinity DataIC50: 520nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 365989BDBM365989(US9873683, Example 38)
Affinity DataIC50: 550nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366061BDBM366061(US9873683, Example 66)
Affinity DataIC50: 550nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366065BDBM366065(US9873683, Example 71)
Affinity DataIC50: 590nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366053BDBM366053(US9873683, Example 53)
Affinity DataIC50: 590nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366046BDBM366046(US9873683, Example 40)
Affinity DataIC50: 630nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366047BDBM366047(US9873683, Example 41)
Affinity DataIC50: 650nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366063BDBM366063(US9873683, Example 68)
Affinity DataIC50: 790nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366070BDBM366070(US9873683, Example 80)
Affinity DataIC50: 1.30E+3nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366052BDBM366052(US9873683, Example 51)
Affinity DataIC50: 1.70E+3nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366068BDBM366068(US9873683, Example 74)
Affinity DataIC50: 2.50E+3nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366066BDBM366066(US9873683, Example 72)
Affinity DataIC50: 3.40E+3nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366051BDBM366051(US9873683, Example 50)
Affinity DataIC50: 3.70E+3nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 86422BDBM86422(NSC_43815 | CAS_61869-08-7 | PAROXETINE | US987368...)
Affinity DataIC50: 4.00E+3nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandChemical structure of BindingDB Monomer ID 366064BDBM366064(US9873683, Example 69)
Affinity DataIC50: 5.40E+3nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent