Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 624
TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283120((R)-(6-(4-chlorophenyl)-1-methyl-8-(1-methyl-1H-py...)
Affinity DataIC50: 87nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
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TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283124((R)-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[...)
Affinity DataIC50: 100nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
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TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283122(US9884874, Compound 13)
Affinity DataIC50: 110nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
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TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283121(US9884874, Compound 12)
Affinity DataIC50: 110nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
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TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283127((R)-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[...)
Affinity DataIC50: 160nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
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TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283109((R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benz...)
Affinity DataIC50: 190nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
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TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283110((R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benz...)
Affinity DataIC50: 220nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
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TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283117((R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benz...)
Affinity DataIC50: 220nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
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TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283115((R)-(6-(4-cyanophenyl)-8-methoxy-1-methyl-4H-benzo...)
Affinity DataIC50: 230nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
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TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283125((R)-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[...)
Affinity DataIC50: 250nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
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TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283118((R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benz...)
Affinity DataIC50: 280nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
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TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283123((R)-(6-(4-chlorophenyl)-8-((2-hydroxyethyl)carbamo...)
Affinity DataIC50: 380nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
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TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283111((R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benz...)
Affinity DataIC50: 390nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
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TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283119((R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benz...)
Affinity DataIC50: 400nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
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TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283112((R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benz...)
Affinity DataIC50: 420nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
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TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283113((R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benz...)
Affinity DataIC50: 900nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283126((R)-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[...)
Affinity DataIC50: 900nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283114((R)-(6-(4-chlorophenyl)-1-methyl-4H-benzo[f][1,2,4...)
Affinity DataIC50: 1.41E+3nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
Go to US Patent