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Found 22 Enz. Inhib. hit(s) with all data for entry = 2697
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334955(US11040966, Example 5.214 | US9732075, Example 5.2...)
Affinity DataIC50:  2nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334973(US11040966, Example 5.36 | US9732075, Example 5.36...)
Affinity DataIC50:  2nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334960(US11040966, Example 5.24 | US9732075, Example 5.24...)
Affinity DataIC50:  2nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334973(US11040966, Example 5.36 | US9732075, Example 5.36...)
Affinity DataIC50:  3nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334955(US11040966, Example 5.214 | US9732075, Example 5.2...)
Affinity DataIC50:  4nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM335102(US11040966, Example 5.277 | US9732075, Example 5.2...)
Affinity DataIC50:  6nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM335031((5-Methyl-2-[1,2,3]triazol-2-yl-phenyl)-[(S)-2-met...)
Affinity DataIC50:  8nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334927(US11040966, Example 5.19 | US9732075, Example 5.19...)
Affinity DataIC50:  9nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334960(US11040966, Example 5.24 | US9732075, Example 5.24...)
Affinity DataIC50:  9nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334959(US11040966, Example 5.23 | US9732075, Example 5.23...)
Affinity DataIC50:  15nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM335023(US11040966, Example 5.82 | US9732075, Example 5.82...)
Affinity DataIC50:  15nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334950(US11040966, Example 5.21 | US9732075, Example 5.21...)
Affinity DataIC50:  18nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334939((5-Methyl-2-[1,2,3]triazol-2-yl-phenyl)-[(S)-2-met...)
Affinity DataIC50:  19nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334927(US11040966, Example 5.19 | US9732075, Example 5.19...)
Affinity DataIC50:  20nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM335102(US11040966, Example 5.277 | US9732075, Example 5.2...)
Affinity DataIC50:  21nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334950(US11040966, Example 5.21 | US9732075, Example 5.21...)
Affinity DataIC50:  22nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM335006(US11040966, Example 5.67 | US9732075, Example 5.67...)
Affinity DataIC50:  23nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM335006(US11040966, Example 5.67 | US9732075, Example 5.67...)
Affinity DataIC50:  27nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM335023(US11040966, Example 5.82 | US9732075, Example 5.82...)
Affinity DataIC50:  27nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334959(US11040966, Example 5.23 | US9732075, Example 5.23...)
Affinity DataIC50:  80nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM335031((5-Methyl-2-[1,2,3]triazol-2-yl-phenyl)-[(S)-2-met...)
Affinity DataIC50:  81nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334939((5-Methyl-2-[1,2,3]triazol-2-yl-phenyl)-[(S)-2-met...)
Affinity DataIC50:  161nMAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent