BindingDB PrimarySearch_ki

Report error Found 826 Enz. Inhib. hit(s) with all data for entry = 2764

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380105(5-ethoxy-2-methyl-N-[4- (4-oxo-3,4- dihydrophthala...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380106(5-methyl-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380106(5-methyl-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380107(N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]py...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380107(N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]py...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380108(N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]py...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380108(N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]py...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380109(N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]im...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380109(N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]im...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380110(5-(benzyloxy)-2-methyl- N-[4-(4-oxo-3,4- dihydroph...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380111(5-hydroxy-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380112(1-ethyl-N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)p...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380112(1-ethyl-N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)p...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380113(4-oxo-N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phe...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380114(4-oxo-N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phe...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380114(4-oxo-N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phe...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380115(N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]-1...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380115(N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]-1...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380119(5-chloro-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380120(N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]-1...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380120(N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]-1...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380121(2-methyl-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380121(2-methyl-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380122(4-methoxy-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380122(4-methoxy-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380123(N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]-1...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380124(5-chloro-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380125(5-fluoro-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380125(5-fluoro-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380126(6-methyl-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380127(1-methyl-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380127(1-methyl-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380128(5-methoxy-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380129(8-chloro-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380130(5-methoxy-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380130(5-methoxy-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380131(7-methyl-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380132(6-methoxy-1-methyl-N- [4-(4-oxo-3,4- dihydrophthal...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380132(6-methoxy-1-methyl-N- [4-(4-oxo-3,4- dihydrophthal...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380133(N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]-6...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380133(N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]-6...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380134(7-methoxy-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380134(7-methoxy-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380135(5-ethoxy-1-methyl-N-[4- (4-oxo-3,4- dihydrophthala...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380135(5-ethoxy-1-methyl-N-[4- (4-oxo-3,4- dihydrophthala...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380136(2-methyl-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380136(2-methyl-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380137(N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]-1...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380137(N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]-1...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

Rho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent

PNG

BDBM380138(N-[4-(4-oxo-3,4- dihydrophthalazin-1- yl)phenyl]im...)

IC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details US Patent

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