Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 3165
TargetCholesterol 24-hydroxylase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM393292(US9963443, Reference Example 21)
Affinity DataIC50: 4.90nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetCholesterol 24-hydroxylase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM393278(US9963443, Reference Example 1)
Affinity DataIC50: 5.40nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetCholesterol 24-hydroxylase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM393291(US9963443, Reference Example 20)
Affinity DataIC50: 6.90nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetCholesterol 24-hydroxylase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM393282(US9963443, Reference Example 4)
Affinity DataIC50: 7.10nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetCholesterol 24-hydroxylase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM393280(US9963443, Reference Example 3)
Affinity DataIC50: 7.40nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetCholesterol 24-hydroxylase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM393279(US9963443, Reference Example 2)
Affinity DataIC50: 8.80nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetCholesterol 24-hydroxylase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM393297(US9963443, Reference Example 26)
Affinity DataIC50: 10nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetCholesterol 24-hydroxylase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM393285(US9963443, Reference Example 11)
Affinity DataIC50: 16nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetCholesterol 24-hydroxylase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM393288(US9963443, Reference Example 14)
Affinity DataIC50: 17nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetCholesterol 24-hydroxylase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM393296(US9963443, Reference Example 23)
Affinity DataIC50: 17nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetCholesterol 24-hydroxylase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM393283(US9963443, Reference Example 5)
Affinity DataIC50: 19nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetCholesterol 24-hydroxylase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM393286(US9963443, Reference Example 13)
Affinity DataIC50: 20nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetCholesterol 24-hydroxylase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM393284(US9963443, Reference Example 10)
Affinity DataIC50: 20nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent