Compile Data Set for Download or QSAR
Report error Found 245 Enz. Inhib. hit(s) with all data for entry = 3293
TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396701BDBM396701(US9981944, Example 46 | 6-(6'-chloro-[2,2'-bipyrid...)
Affinity DataIC50: 0.400nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396673BDBM396673(US9981944, Example 19 | 6-(5'-fluoro-6'-methyl-[2,...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396683BDBM396683(US9981944, Example 29 | 6-(6'-(difluoromethyl)-[2,...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396672BDBM396672(US9981944, Example 18 | 6-(6'-(trifluoromethyl)-[2...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396689BDBM396689(US9981944, Example 35 | 6-(6'-cyclopropyl-[2,2'-bi...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396687BDBM396687(US9981944, Example 33 | 6-(6'-methoxy-[2,2'-bipyri...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396730BDBM396730(US9981944, Example 76 | N-(6-(6'-methyl-[2,2'-bipy...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396738BDBM396738(US9981944, Example 84 | 6-(6'-(difluoromethyl)-5-f...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396736BDBM396736(US9981944, Example 82 | 6-(5-fluoro-6'-methyl-[2,2...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396766BDBM396766(US9981944, Example 111 | 6-(6'-isopropyl-[2,2'-bip...)
Affinity DataIC50: 2nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396726BDBM396726(US9981944, Example 72 | methyl-6-(6'-methyl-[2,2'-...)
Affinity DataIC50: 2nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396740BDBM396740(US9981944, Example 85 | 6-(5,5'-difluoro-6'-methyl...)
Affinity DataIC50: 2nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396764BDBM396764(US9981944, Example 109 | 6-(6'-(difluoromethyl)-[2...)
Affinity DataIC50: 2nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396772BDBM396772(US9981944, Example 117 | 5-(5'-fluoro-6'-methyl-[2...)
Affinity DataIC50: 2nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396765BDBM396765(US9981944, Example 110 | 6-(5'-fluoro-6'-methyl-[2...)
Affinity DataIC50: 2nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396753BDBM396753(US9981944, Example 98 | 6-(5-amino-6'-methyl-[2,2'...)
Affinity DataIC50: 2nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396770BDBM396770(US9981944, Example 115 | 5-(6'-(difluoromethyl)-[2...)
Affinity DataIC50: 3nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396760BDBM396760(US9981944, Example 105 | 6-(6'-(difluoromethyl)-[2...)
Affinity DataIC50: 3nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396702BDBM396702(US9981944, Example 47 | 6-(6'-methyl-[2,2'-bipyrid...)
Affinity DataIC50: 3nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396725BDBM396725(US9981944, Example 70 | N-(2-methoxyethyl)-6-(6'-m...)
Affinity DataIC50: 4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396758BDBM396758(US9981944, Example 103 | 6-(5'-fluoro-6'-methyl-[2...)
Affinity DataIC50: 4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396692BDBM396692(US9981944, Example 37 | 6-(6'-fluoro-[2,2'-bipyrid...)
Affinity DataIC50: 4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396722BDBM396722(US9981944, Example 67 | 6-(6'-methyl-[2,2'-bipyrid...)
Affinity DataIC50: 4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396723BDBM396723(US9981944, Example 68 | N-(2,2-difluoroethyl)-6-(6...)
Affinity DataIC50: 4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396731BDBM396731(US9981944, Example 77 | N-(6-(5'-fluoro-6'-methyl-...)
Affinity DataIC50: 4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396754BDBM396754(US9981944, Example 99 | 6-(5-amino-6'-methyl-[2,2'...)
Affinity DataIC50: 4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396761BDBM396761(US9981944, Example 106 | 6-(6'-cyclopropyl-[2,2'-b...)
Affinity DataIC50: 4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396756BDBM396756(US9981944, Example 101 | 6-(4-amino-6'-methyl-[2,2...)
Affinity DataIC50: 5nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396675BDBM396675(US9981944, Example 21 | 6-(5'-fluoro-[2,2'-bipyrid...)
Affinity DataIC50: 5nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396752BDBM396752(US9981944, Example 97 | 6-(5-acetamido-6'-methyl-[...)
Affinity DataIC50: 5nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396676BDBM396676(US9981944, Example 22 | 6-(4'-fluoro-[2,2'-bipyrid...)
Affinity DataIC50: 5nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396793BDBM396793(US9981944, Example 138 | 5-(6'-methyl-[2,2'-bipyri...)
Affinity DataIC50: 5nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396775BDBM396775(US9981944, Example 120 | 5-(6'-methyl-[2,2'-bipyri...)
Affinity DataIC50: 6nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396694BDBM396694(US9981944, Example 39 | 6-([2,2'-bipyridin]-3- yl)...)
Affinity DataIC50: 6nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396724BDBM396724(US9981944, Example 69 | 6-(6'-methyl-[2,2'-bipyrid...)
Affinity DataIC50: 7nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396792BDBM396792(US9981944, Example 137 | 5-(5'-fluoro-6'-methyl-[2...)
Affinity DataIC50: 8nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396682BDBM396682(US9981944, Example 28 | 6-(6'-(difluoromethyl)-[2,...)
Affinity DataIC50: 9nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396617BDBM396617(US9981944, Example 17 | 6-(6'-methoxy-[2,2'-bipyri...)
Affinity DataIC50: 9nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396762BDBM396762(US9981944, Example 107 | 6-(6'-ethyl-[2,2'-bipyrid...)
Affinity DataIC50: 9nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396768BDBM396768(US9981944, Example 113 | 6-(6'-methyl-[2,2'-bipyri...)
Affinity DataIC50: 9nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396559BDBM396559(US9981944, Example 15 | 6-(5'-fluoro-6'-methyl-[2,...)
Affinity DataIC50: 10nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396404BDBM396404(US9981944, Example 14 | 6-(6'-(trifluoromethyl)-[2...)
Affinity DataIC50: 11nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396767BDBM396767(US9981944, Example 112 | 6-(5'-fluoro-6'-methyl-[2...)
Affinity DataIC50: 12nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396743BDBM396743(US9981944, Example 88 | 6-(6'-(difluoromethyl)-6-m...)
Affinity DataIC50: 13nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396771BDBM396771(US9981944, Example 116 | 5-(5'-fluoro-[2,2'-bipyri...)
Affinity DataIC50: 14nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396785BDBM396785(US9981944, Example 130 | ethyl 5-(5'-fluoro-6'-met...)
Affinity DataIC50: 14nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396742BDBM396742(US9981944, Example 87 | 6-(6,6'-dimethyl-[2,2'-bip...)
Affinity DataIC50: 15nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396791BDBM396791(US9981944, Example 136 | 5-(6'-(trifluoromethyl)-[...)
Affinity DataIC50: 15nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396686BDBM396686(US9981944, Example 32 | 6-(6'-isopropyl-[2,2'-bipy...)
Affinity DataIC50: 16nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 396735BDBM396735(US9981944, Example 81 | 6-(5-fluoro-6'-methyl-[2,2...)
Affinity DataIC50: 16nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

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