Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 3329
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397125BDBM397125(US9987259, Example 18 | N-[(3R)-1-azabicyclo[2.2.2...)
Affinity DataEC50: <100nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397118BDBM397118(US9987259, Example 11 | N-[(3R)-1-azabicyclo[2.2.2...)
Affinity DataEC50: <100nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397121BDBM397121(US9987259, Example 14 | N-[(3R)-1-azabicyclo[2.2.2...)
Affinity DataEC50: <100nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397133BDBM397133(US9987259, Example 26 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50: <100nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397111BDBM397111(US9987259, Example 1 | N-(1-azabicyclo[2.2.2]octan...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397112BDBM397112(US9987259, Example 2 | N-[(3R)-1-azabicyclo[2.2.2]...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397113BDBM397113(US9987259, Example 3 | N-[(3S)-1-azabicyclo[2.2.2]...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397138BDBM397138(US9987259, Example 33 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397134BDBM397134(US9987259, Example 27 | N-[(3R)-1-azabicyclo[2.2.2...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397136BDBM397136(US9987259, Example 29 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397130BDBM397130(US9987259, Example 23 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397131BDBM397131(US9987259, Example 24 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397126BDBM397126(US9987259, Example 19 | N-[(3S)-1-azabicyclo[2.2.2...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397127BDBM397127(US9987259, Example 20 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397128BDBM397128(US9987259, Example 21 | N-[(3R)-1-azabicyclo[2.2.2...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397122BDBM397122(US9987259, Example 15 | N-[(3S)-1-azabicyclo[2.2.2...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397123BDBM397123(US9987259, Example 16 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397124BDBM397124(US9987259, Example 17 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397120BDBM397120(US9987259, Example 13 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397115BDBM397115(US9987259, Example 7 | N-(1-azabicyclo[2.2.2]octan...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397117BDBM397117(US9987259, Example 10 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397129BDBM397129(US9987259, Example 22 | N-[(3S)-1-azabicyclo[2.2.2...)
Affinity DataEC50:  750nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397119BDBM397119(US9987259, Example 12 | N-[(3S)-1-azabicyclo[2.2.2...)
Affinity DataEC50:  750nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397132BDBM397132(US9987259, Example 25 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  750nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397139BDBM397139(US9987259, Example 42 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50: >1.00E+3nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397140BDBM397140(US9987259, Example 45 | (1-azabicyclo[2.2.2]octan-...)
Affinity DataEC50: >1.00E+3nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397141BDBM397141(US9987259, Example 46 | US10456385, Example 46)
Affinity DataEC50: >1.00E+3nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397135BDBM397135(US9987259, Example 28 | N-[(3S)-1-azabicyclo[2.2.2...)
Affinity DataEC50: >1.00E+3nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397137BDBM397137(US9987259, Example 30 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50: >1.00E+3nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397114BDBM397114(US9987259, Example 6 | N-(1-azabicyclo[2.2.2]octan...)
Affinity DataEC50: >1.00E+3nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 397116BDBM397116(US9987259, Example 9 | N-(1-azabicyclo[2.2.2]octan...)
Affinity DataEC50: >1.00E+3nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent