Compile Data Set for Download or QSAR
Report error Found 122 Enz. Inhib. hit(s) with all data for entry = 9191
TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194790BDBM194790(US9206167, 12 | US9206167, 11 | USRE48059, Compoun...)
Affinity DataKi:  0.100nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194790BDBM194790(US9206167, 12 | US9206167, 11 | USRE48059, Compoun...)
Affinity DataKi:  0.100nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194794BDBM194794(US9206167, 15 | USRE48059, Compound of Example 15)
Affinity DataKi:  0.200nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 448338BDBM448338(USRE48059, Compound of Example 139)
Affinity DataKi:  0.200nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194780BDBM194780(US9206167, 1 | brexpiprazole | 7-(4-(4-(1-benzothi...)
Affinity DataKi:  0.200nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 448330BDBM448330(USRE48059, Compound of Example 90)
Affinity DataKi:  0.400nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194789BDBM194789(US9206167, 10 | USRE48059, Compound of Example 10)
Affinity DataKi:  0.400nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194786BDBM194786(US9206167, 7 | USRE48059, Compound of Example 7)
Affinity DataKi:  0.5nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194783BDBM194783(US9206167, 4 | USRE48059, Compound of Example 4)
Affinity DataKi:  0.5nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194782BDBM194782(US9206167, 3 | USRE48059, Compound of Example 3)
Affinity DataKi:  0.5nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194787BDBM194787(US9206167, 8 | USRE48059, Compound of Example 8)
Affinity DataKi:  0.600nMAssay Description:5-HT2A: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-Ketanserin (final concentration 1 to 3 nM), 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194784BDBM194784(US9206167, 5 | USRE48059, Compound of Example 5)
Affinity DataKi:  0.600nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194795BDBM194795(US9206167, 16 | USRE48059, Compound of Example 16)
Affinity DataKi:  0.700nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194808BDBM194808(US9206167, 30 | USRE48059, Compound of Example 30 ...)
Affinity DataKi:  0.700nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194802BDBM194802(US9206167, 23 | USRE48059, Compound of Example 23)
Affinity DataKi:  0.700nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 448346BDBM448346(USRE48059, Compound of Example 190)
Affinity DataKi:  0.800nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 448327BDBM448327(USRE48059, Compound of Example 81)
Affinity DataKi:  0.800nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194785BDBM194785(US9206167, 6 | USRE48059, Compound of Example 6)
Affinity DataKi:  0.800nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 448322BDBM448322(BDBM448323 | USRE48059, Compound of Example 68)
Affinity DataKi:  0.800nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194800BDBM194800(US9206167, 21 | USRE48059, Compound of Example 21)
Affinity DataKi:  1nMAssay Description:5-HT2A: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-Ketanserin (final concentration 1 to 3 nM), 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194814BDBM194814(US9206167, 36 | USRE48059, Compound of Example 36)
Affinity DataKi:  1nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 448322BDBM448322(BDBM448323 | USRE48059, Compound of Example 68)
Affinity DataKi:  1nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194811BDBM194811(US9206167, 33 | USRE48059, Compound of Example 33)
Affinity DataKi:  1.10nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194798BDBM194798(US9206167, 19 | USRE48059, Compound of Example 19)
Affinity DataKi:  1.20nMAssay Description:5-HT2A: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-Ketanserin (final concentration 1 to 3 nM), 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194812BDBM194812(US9206167, 34 | USRE48059, Compound of Example 34)
Affinity DataKi:  1.20nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194807BDBM194807(US9206167, 28 | USRE48059, Compound of Example 28 ...)
Affinity DataKi:  1.20nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194817BDBM194817(US9206167, 39 | USRE48059, Compound of Example 39)
Affinity DataKi:  1.20nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194816BDBM194816(US9206167, 38 | USRE48059, Compound of Example 38)
Affinity DataKi:  1.20nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194798BDBM194798(US9206167, 19 | USRE48059, Compound of Example 19)
Affinity DataKi:  1.20nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 448324BDBM448324(USRE48059, Compound of Example 73 | USRE48059, Com...)
Affinity DataKi:  1.30nMAssay Description:5-HT2A: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-Ketanserin (final concentration 1 to 3 nM), 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 448337BDBM448337(USRE48059, Compound of Example 128)
Affinity DataKi:  1.30nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 448334BDBM448334(USRE48059, Compound of Example 117)
Affinity DataKi:  1.30nMAssay Description:5-HT2A: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-Ketanserin (final concentration 1 to 3 nM), 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 448331BDBM448331(USRE48059, Compound of Example 91)
Affinity DataKi:  1.40nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194809BDBM194809(US9206167, 31 | USRE48059, Compound of Example 31)
Affinity DataKi:  1.40nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194781BDBM194781(US9206167, 2 | USRE48059, Compound of Example 2)
Affinity DataKi:  1.5nMAssay Description:5-HT2A: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-Ketanserin (final concentration 1 to 3 nM), 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 448326BDBM448326(USRE48059, Compound of Example 80)
Affinity DataKi:  1.5nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194812BDBM194812(US9206167, 34 | USRE48059, Compound of Example 34)
Affinity DataKi:  1.5nMAssay Description:5-HT2A: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-Ketanserin (final concentration 1 to 3 nM), 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194810BDBM194810(US9206167, 32 | USRE48059, Compound of Example 32)
Affinity DataKi:  1.5nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194799BDBM194799(US9206167, 20 | USRE48059, Compound of Example 20)
Affinity DataKi:  1.5nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194813BDBM194813(US9206167, 35 | USRE48059, Compound of Example 35)
Affinity DataKi:  1.60nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 448345BDBM448345(USRE48059, Compound of Example 188)
Affinity DataKi:  1.60nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 448332BDBM448332(USRE48059, Compound of Example 92)
Affinity DataKi:  1.70nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194802BDBM194802(US9206167, 23 | USRE48059, Compound of Example 23)
Affinity DataKi:  1.70nMAssay Description:5-HT2A: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-Ketanserin (final concentration 1 to 3 nM), 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194819BDBM194819(US9206167, 41 | USRE48059, Compound of Example 41)
Affinity DataKi:  1.90nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194815BDBM194815(US9206167, 37 | USRE48059, Compound of Example 37)
Affinity DataKi:  1.90nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 448329BDBM448329(USRE48059, Compound of Example 85)
Affinity DataKi:  2nMAssay Description:Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194808BDBM194808(US9206167, 30 | USRE48059, Compound of Example 30 ...)
Affinity DataKi:  2nMAssay Description:5-HT2A: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-Ketanserin (final concentration 1 to 3 nM), 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194813BDBM194813(US9206167, 35 | USRE48059, Compound of Example 35)
Affinity DataKi:  2.10nMAssay Description:5-HT2A: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-Ketanserin (final concentration 1 to 3 nM), 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194814BDBM194814(US9206167, 36 | USRE48059, Compound of Example 36)
Affinity DataKi:  2.10nMAssay Description:5-HT2A: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-Ketanserin (final concentration 1 to 3 nM), 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194790BDBM194790(US9206167, 12 | US9206167, 11 | USRE48059, Compoun...)
Affinity DataKi:  2.10nMAssay Description:5-HT2A: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-Ketanserin (final concentration 1 to 3 nM), 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

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