Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 792 Enz. Inhib. hit(s) with all data for entry = 10419
TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534434(WO2022086828, Example 170)
Affinity DataIC50:  0.100nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534472(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.200nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534402(WO2022086828, Example 138)
Affinity DataIC50:  0.200nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534450(WO2022086828, Example 186)
Affinity DataIC50:  0.200nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534377(5-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.300nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534328(WO2022086828, Example 55)
Affinity DataIC50:  0.300nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534325(WO2022086828, Example 52)
Affinity DataIC50:  0.300nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534323(WO2022086828, Example 50)
Affinity DataIC50:  0.300nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534427(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.300nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534461(3 -(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-y...)
Affinity DataIC50:  0.300nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534452(WO2022086828, Example 188)
Affinity DataIC50:  0.300nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534445(WO2022086828, Example 181)
Affinity DataIC50:  0.300nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534443(WO2022086828, Example 179)
Affinity DataIC50:  0.300nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534440(WO2022086828, Example 176)
Affinity DataIC50:  0.300nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534432(WO2022086828, Example 168)
Affinity DataIC50:  0.300nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534424(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.300nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534579((S)-3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-...)
Affinity DataIC50:  0.400nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534448(WO2022086828, Example 184)
Affinity DataIC50:  0.400nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534288(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.400nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534447(WO2022086828, Example 183)
Affinity DataIC50:  0.400nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534480(WO2022086828, Example 216)
Affinity DataIC50:  0.400nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534567(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.400nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534329(WO2022086828, Example 56)
Affinity DataIC50:  0.400nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534380(5-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.400nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534497(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534547(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.5nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534554(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534562(3-(2-amino-[1,2,4]triazolo[1,5-α]pyri din-7-y...)
Affinity DataIC50:  0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534326(WO2018148626, Example 152 | WO2022086828, Example ...)
Affinity DataIC50:  0.5nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534554(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.5nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534302(WO2022086828, Example 30)
Affinity DataIC50:  0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534358(WO2022086828, Example 85)
Affinity DataIC50:  0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534378(5-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534379(5-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534399(WO2022086828, Example 135)
Affinity DataIC50:  0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534326(WO2018148626, Example 152 | WO2022086828, Example ...)
Affinity DataIC50:  0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534341(WO2022086828, Example 68)
Affinity DataIC50:  0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534419((S)-3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-...)
Affinity DataIC50:  0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534410((S)-5-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-...)
Affinity DataIC50:  0.600nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534285(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.600nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534275(WO2022086828, Example 3)
Affinity DataIC50:  0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534404(WO2022086828, Example 140)
Affinity DataIC50:  0.600nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534410((S)-5-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-...)
Affinity DataIC50:  0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534471(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534342(WO2022086828, Example 69)
Affinity DataIC50:  0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534564(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534569(WO2022086828, Example 305)
Affinity DataIC50:  0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534463(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534449(WO2022086828, Example 185)
Affinity DataIC50:  0.600nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534497(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50:  0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022086828


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