Found 25 Enz. Inhib. hit(s) with all data for entry = 11072 TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 0.25nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 0.300nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 0.390nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 0.610nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 1.19nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 1.63nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 1.65nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 1.98nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 2.34nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 3.06nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 3.34nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 3.48nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 4.73nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 6.36nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 9.23nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 14nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 15nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 18nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 18nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 23nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 24nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 27nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 47nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 64nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
WIPO
Blueprint Medicines
WIPO
Affinity DataIC50: 121nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
