Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 648
TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681168BDBM681168(N-(4-((R*)-2-(3-Chloro-2-fluorophenyl)propyl)-6-((...)
Affinity DataIC50: 68nMAssay Description:cell-based assay using HEK293-gfpPLD2 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681308BDBM681308(US20240199558, Example 144 | N-(4-((R*)-2-(2,3-Dif...)
Affinity DataIC50: 104nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681252BDBM681252(US20240199558, Example 88 | N-(4-(((R)-1-Hydroxy-4...)
Affinity DataIC50: 115nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681310BDBM681310(US20240199558, Example 146 | N-(4-((R*)-2-(2-Fluor...)
Affinity DataIC50: 180nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681248BDBM681248(US20240199558, Example 84 | N-(4-((R*)-2-(4-Chloro...)
Affinity DataIC50: 348nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681165BDBM681165(N-(4-((R*)-2-(3,4-Dichlorophenyl)propyl)-6-(((R)-1...)
Affinity DataIC50: 362nMAssay Description:cell-based assay using HEK293-gfpPLD2 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681247BDBM681247(US20240199558, Example 83 | N-(4-((S*)-2-(4-Chloro...)
Affinity DataIC50: 424nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681307BDBM681307(US20240199558, Example 143 | N-(4-((S*)-2-(2,3-Dif...)
Affinity DataIC50: 430nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681167BDBM681167(N-(4-((S*)-2-(3-Chloro-2-fluorophenyl)propyl)-6-((...)
Affinity DataIC50: 448nMAssay Description:cell-based assay using HEK293-gfpPLD2 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681245BDBM681245(US20240199558, Example 81 | N-(4-((R*)-2-(2-Fluoro...)
Affinity DataIC50: 470nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681311BDBM681311(US20240199558, Example 148 | N-(4-(((R)-1-Hydroxy-...)
Affinity DataIC50: 484nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681246BDBM681246(US20240199558, Example 82 | N-(4-((S*)-2-(2-Fluoro...)
Affinity DataIC50: 566nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681309BDBM681309(US20240199558, Example 145 | N-(4-((S*)-2-(2-Fluor...)
Affinity DataIC50: 637nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 42044BDBM42044(N-(4-((R)-2-(2-Chloropyridin-4-yl)propyl)-6-(((R)-...)
Affinity DataIC50: 682nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681249BDBM681249(US20240199558, Example 85 | N-(4-((R*)-2-(2-Fluoro...)
Affinity DataIC50: 691nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681240BDBM681240(US20240199558, Example 76 | N-(4-(((R)-1-Hydroxy-4...)
Affinity DataIC50: 886nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681169BDBM681169(N-(4-((S*)-2-(2,4-Difluorophenyl)propyl)-6-(((R)-1...)
Affinity DataIC50: 895nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681170BDBM681170(N-(4-((R*)-2-(2,4-Difluorophenyl)propyl)-6-(((R)-1...)
Affinity DataIC50: 948nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681253BDBM681253(US20240199558, Example 89 | N-(4-(2-(2-Fluoropheny...)
Affinity DataIC50: 987nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681312BDBM681312(US20240199558, Example 150 | N-(4-((R*)-2-(5-Chlor...)
Affinity DataIC50: 1.53E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681231BDBM681231(N-(4-(2-(2-Ethoxypyridin-4-yl)propyl)-6-(((R)-1-hy...)
Affinity DataIC50: 1.83E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681176BDBM681176(N-(4-((R*)-2-(2-Cyclopropylpyrimidin-5-yl)propyl)-...)
Affinity DataIC50: 1.86E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 41739BDBM41739(N-(4-((S)-2-(3,4-Dichlorophenyl)propyl)-6-(((R)-1-...)
Affinity DataIC50: 1.97E+3nMAssay Description:cell-based assay using HEK293-gfpPLD2 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681243BDBM681243(US20240199558, Example 79 | N-(4-((R*)-2-(4-Fluoro...)
Affinity DataIC50: 2.47E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681179BDBM681179(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50: 2.99E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681177BDBM681177(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50: 4.25E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681181BDBM681181(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50: 4.37E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681244BDBM681244(US20240199558, Example 80 | N-(4-((S*)-2-(4-Fluoro...)
Affinity DataIC50: 4.90E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681239BDBM681239(US20240199558, Example 75 | N-(4-(((R)-1-Hydroxy-4...)
Affinity DataIC50: 5.18E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681216BDBM681216(N-(4-((R*)-2-(2,6-Dimethoxypyridin-3-yl)propyl)-6-...)
Affinity DataIC50: 5.52E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 42272BDBM42272(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681171BDBM681171(N-(4-((R*)-2-(5-Fluoro-6-methoxypyridin-3-yl)propy...)
Affinity DataIC50: 1.00E+4nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681173BDBM681173(N-(4-((R*)-2-(5-Chloro-6-methoxypyridin-3-yl)propy...)
Affinity DataIC50: 1.00E+4nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681217BDBM681217(N-(4-((S*)-2-(2,6-Dimethoxypyridin-3-yl)propyl)-6-...)
Affinity DataIC50: 1.10E+4nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681189BDBM681189(N-(4-((S*)-2-(2-Chloropyridin-4-yl)propyl)-6-(((R)...)
Affinity DataIC50: 1.35E+4nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681182BDBM681182(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50: 1.67E+4nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681172BDBM681172(N-(4-((S*)-2-(5-Fluoro-6-methoxypyridin-3-yl)propy...)
Affinity DataIC50: 2.00E+4nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681174BDBM681174(N-(4-((S*)-2-(5-Chloro-6-methoxypyridin-3-yl)propy...)
Affinity DataIC50: 2.00E+4nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681175BDBM681175(N-(4-((S*)-2-(2-Cyclopropylpyrimidin-5-yl)propyl)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 681180BDBM681180(N-(4-(((R)-1-Hydroxy-4-methylpentan-2-yl)amino)-6-...)
Affinity DataIC50: 3.00E+4nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetCX3C chemokine receptor 1(Human)
SE-151 85 S�dert�lje

WIPO
LigandChemical structure of BindingDB Monomer ID 42274BDBM42274(N-(4-((S)-2-(5-Chloropyridin-2-yl)propyl)-6-(((R)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent