Compile Data Set for Download or QSAR
Report error Found 167 Enz. Inhib. hit(s) with all data for entry = 794
TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42292BDBM42292((R)-2-(3-((2-fluoroethoxy)methyl)-4-(pyrimidin-4-y...)
Affinity DataKi:  0.320nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42277BDBM42277((R,E)-2-(3-((2-fluoroethoxy)methyl)-4-(pyrimidin-2...)
Affinity DataKi:  0.420nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42289BDBM42289((R)-2-(2-((2-fluoroethoxy)methyl)-4-(5-((6-(1-meth...)
Affinity DataKi:  0.449nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42047BDBM42047((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  0.5nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 41742BDBM41742((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  0.5nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42266BDBM42266((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  0.5nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42057BDBM42057((R,E)-(1-(5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)v...)
Affinity DataKi:  0.5nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42276BDBM42276(1-((2-((R)-4-(5-((E)-2-(6-(1H-imidazol-1-yl)pyridi...)
Affinity DataKi:  0.520nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42282BDBM42282((R)-2-(2-((2-fluoroethoxy)methyl)-4-(5-((2-(1-meth...)
Affinity DataKi:  0.570nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42273BDBM42273((R,E)-5-(2-(6-(1-(2-fluoroethyl)-1H-pyrazol-4-yl)p...)
Affinity DataKi:  0.620nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42295BDBM42295((R)-2-(4-(5-((2-(1-(fluoromethyl)-1H-pyrazol-4-yl)...)
Affinity DataKi:  0.640nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42285BDBM42285((R)-2-(4-(5-((6-(1-(2-fluoroethyl)-1H-pyrazol-4-yl...)
Affinity DataKi:  0.694nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42053BDBM42053((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  0.700nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42341BDBM42341((R)-2-(4-(6-fluoropyrimidin-4-yl)-3-(methoxymethyl...)
Affinity DataKi:  0.760nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42280BDBM42280((R,E)-5-(5-(2-(2-(3-((2-fluoroethoxy)methyl)-4-(py...)
Affinity DataKi:  0.780nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42279BDBM42279((R,E)-5-(5-(2-(2-(3-((2-fluoroethoxy)methyl)-4-(1,...)
Affinity DataKi:  0.800nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 41950BDBM41950((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  0.800nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42339BDBM42339((R)-5-(2-fluoroethoxy)-2-(2-(methoxymethyl)-4-(5-(...)
Affinity DataKi:  0.830nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42334BDBM42334((S)-2-(4-(5-((2-(1-(2-fluoroethyl)-1H-pyrazol-4-yl...)
Affinity DataKi:  0.890nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42287BDBM42287((R)-5-(5-((2-(3-((2-(2-fluoroethoxy)ethoxy)methyl)...)
Affinity DataKi:  0.897nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 41741BDBM41741((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  0.900nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42267BDBM42267((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  0.900nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42043BDBM42043((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  0.900nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42058BDBM42058((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  0.900nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42293BDBM42293((R)-2-(1 -(2-fluoroethyl)-1H-pyrazol-4-yl)-5-((2-(...)
Affinity DataKi:  0.910nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42304BDBM42304(3-(((R)-4-(5-((6-(1H-imidazol-1-yl)pyridin-3-yl)et...)
Affinity DataKi:  0.913nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42320BDBM42320((R)-7-(5-((2-(3-((2-fluoroethoxy)methyl)-4-(1,3,5-...)
Affinity DataKi:  0.915nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42271BDBM42271((R,E)-5-(5-(2-(2-(3-((2-fluoroethoxy)methyl)-4-(py...)
Affinity DataKi:  0.940nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42335BDBM42335((R)-5-fluoro-2-(4-(5-((2-(1-(2-fluoroethyl)-1H-pyr...)
Affinity DataKi:  0.990nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42068BDBM42068((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  1nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42265BDBM42265((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  1nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42039BDBM42039((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  1nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42041BDBM42041((R,E)-(1-(5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)v...)
Affinity DataKi:  1nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42332BDBM42332((R)-2-(1-(2-fluoroethyl)-1H-pyrazol-4-yl)-5-((2-(4...)
Affinity DataKi:  1.05nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42307BDBM42307(1-(4-(6-fluoropyrimidin-4-yl)-1-(5-((6-(oxazol-5-y...)
Affinity DataKi:  1.10nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42037BDBM42037((R)-5-((6-(1H-imidazol-1-yl)pyridin-3-yl)ethynyl)-...)
Affinity DataKi:  1.10nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 41949BDBM41949((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  1.10nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42321BDBM42321((R)-5-((6-(4-(2H-1,2,3-triazol-2-yl)piperidin-1-yl...)
Affinity DataKi:  1.15nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42327BDBM42327((R)-2-(4-(5-((6-(6-fluoropyrimidin-4-yl)pyridin-3-...)
Affinity DataKi:  1.18nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 41743BDBM41743((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  1.20nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42054BDBM42054((R,E)-(1-(-(2-(6-(1 H-imidazol-1-yl)pyridin-3-yl)v...)
Affinity DataKi:  1.20nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42281BDBM42281((R,E)-2-(2-((2-fluoroethoxy)methyl)-4-(5-(2-(2-(1-...)
Affinity DataKi:  1.22nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42284BDBM42284((R)-2-(4-(5-((2-(1-(2-fluoroethyl)-1H-pyrazol-4-yl...)
Affinity DataKi:  1.29nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42066BDBM42066((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  1.30nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42052BDBM42052((R,E)-7-(4-(6-(2-(6-(1H-pyrazol-1-yl)pyridin-3-yl)...)
Affinity DataKi:  1.30nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42040BDBM42040((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  1.30nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42049BDBM42049((R,E)-6-(2-(2-(2-(methoxymethyl)-4-(pyridin-2-yl)p...)
Affinity DataKi:  1.40nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42328BDBM42328((R)-2-(3-((2-(2-(2-fluoroethoxy)ethoxy)ethoxy)meth...)
Affinity DataKi:  1.43nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42301BDBM42301((S)-5-(5-((2-(3-((2-fluoroethoxy)methyl)-4-(1,3,5-...)
Affinity DataKi:  1.48nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42300BDBM42300((R)-4-(4-(5-((6-(1H-imidazol-1-yl)pyridin-3-yl)eth...)
Affinity DataKi:  1.49nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent

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