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Found
79
Enz. Inhib. hit(s) with all data for entry = 13312
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776382
((3R,4S)-4-(4-chlorophenyl)-1-(3-pyridazin-4-yl-1H-...)
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Affinity Data
IC50: 30nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776374
([(3R,4S)-3-(4-chlorophenyl)-4-methyl-pyrrolidin-1-...)
Copy SMILES
Affinity Data
IC50: 51nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776350
([(3S)-3-(3,4-difluorophenyl)pyrrolidin-1-yl]-(3-py...)
Copy SMILES
Affinity Data
IC50: 57nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776359
((4-chloro-3-pyridazin-4-yl-1H-pyrazol-5-yl)-[(3R)-...)
Copy SMILES
Affinity Data
IC50: 68nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776383
([(3R,4S)-3-(3,4-difluorophenyl)-4-methyl-pyrrolidi...)
Copy SMILES
Affinity Data
IC50: 72nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776369
([(3R,4S)-3-(4-chlorophenyl)-4-(hydroxymethyl)pyrro...)
Copy SMILES
Affinity Data
IC50: 72nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776348
([3-(4-chloro-3-fluoro-phenyl)pyrrolidin-1-yl]-(3-p...)
Copy SMILES
Affinity Data
IC50: 73nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776362
([(3S,4R)-3-(4-bromophenyl)-4-methyl-pyrrolidin-1-y...)
Copy SMILES
Affinity Data
IC50: 84nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776387
([(3S,4R)-3-(3,4-difluorophenyl)-4-(hydroxymethyl)p...)
Copy SMILES
Affinity Data
IC50: 93nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776372
([(3R)-3-(4-chlorophenyl)pyrrolidin-1-yl]-(4-fluoro...)
Copy SMILES
Affinity Data
IC50: 95nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776319
([3-(5-chloro-2-thienyl)pyrrolidin-1-yl]-(3-pyridaz...)
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Affinity Data
IC50: 98nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776326
([3-(3,4-difluorophenyl)pyrrolidin-1-yl]-(3-pyridaz...)
Copy SMILES
Affinity Data
IC50: 105nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776353
([3-(5-bromo-2-thienyl)pyrrolidin-1-yl]-(3-pyridazi...)
Copy SMILES
Affinity Data
IC50: 114nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776356
((4-chloro-3-pyridazin-4-yl-1H-pyrazol-5-yl)-[3-(3,...)
Copy SMILES
Affinity Data
IC50: 142nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776339
([(3R,4S)-3-(4-chlorophenyl)-4-hydroxy-pyrrolidin-1...)
Copy SMILES
Affinity Data
IC50: 172nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776351
([(3R)-3-(3,4-difluorophenyl)pyrrolidin-1-yl]-(3-py...)
Copy SMILES
Affinity Data
IC50: 183nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776355
([3-(4-bromophenyl)-4-methyl-pyrrolidin-1-yl]-(3-py...)
Copy SMILES
Affinity Data
IC50: 188nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776313
([3-(4-chlorophenyl)pyrrolidin-1-yl]-(3-pyridazin-4...)
Copy SMILES
Affinity Data
IC50: 191nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776335
([(3R)-3-(4-chlorophenyl)pyrrolidin-1-yl]-[3-(4-pyr...)
Copy SMILES
Affinity Data
IC50: 194nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776318
({3-(5-chloro-2-thienyl)pyrrolidin-1-yl]-[3-(4-pyri...)
Copy SMILES
Affinity Data
IC50: 194nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776377
([(3R,4S)-3-(4-chlorophenyl)-4-[(1R)-1-hydroxyethyl...)
Copy SMILES
Affinity Data
IC50: 196nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776379
([(3S)-3-(4-chloro-2-thienyl)pyrrolidin-1-yl]-(3-py...)
Copy SMILES
Affinity Data
IC50: 214nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776376
([(3R,4S)-3-(4-chlorophenyl)-4-[(1S)-1-hydroxyethyl...)
Copy SMILES
Affinity Data
IC50: 217nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776367
((4-bromo-3-pyridazin-4-yl-1H-pyrazol-5-yl)-[(3R)-3...)
Copy SMILES
Affinity Data
IC50: 340nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776330
([(3R,4S)-3-(4-chlorophenyl)-4-hydroxy-pyrrolidin-1...)
Copy SMILES
Affinity Data
IC50: 351nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776358
((4-chloro-3-pyridazin-4-yl-1H-pyrazol-5-yl)-[(3S)-...)
Copy SMILES
Affinity Data
IC50: 379nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776310
([3-(4-Chlorophenyl)pyrrolidin-1-yl]-[3-(4-pyridyl)...)
Copy SMILES
Affinity Data
IC50: 387nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776314
([3-(4-chlorophenyl)pyrrolidin-1-yl]-(4-methyl-3-py...)
Copy SMILES
Affinity Data
IC50: 427nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776317
([3-(2-chloro-4-fluoro-phenyl)pyrrolidin-1-yl]-[3-(...)
Copy SMILES
Affinity Data
IC50: 458nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776360
([3-(4-bromophenyl)pyrrolidin-1-yl]-(3-pyridazin-4-...)
Copy SMILES
Affinity Data
IC50: 461nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776328
([3-(6-chloro-3-pyridyl)pyrrolidin-1-yl]-(3-pyridaz...)
Copy SMILES
Affinity Data
IC50: 469nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776373
([(3S)-3-(4-chlorophenyl)pyrrolidin-1-yl]-(4-fluoro...)
Copy SMILES
Affinity Data
IC50: 492nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776365
([(3S)-3-(4-chlorophenyl)pyrrolidin-1-yl]-[3-(3-met...)
Copy SMILES
Affinity Data
IC50: 500nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776384
([(3R,4S)-3-(4-chlorophenyl)-4-fluoro-pyrrolidin-1-...)
Copy SMILES
Affinity Data
IC50: 506nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776341
([3-(4-chlorophenyl)-2,3,3a,4,5,6,7,7a-octahydroind...)
Copy SMILES
Affinity Data
IC50: 521nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776381
((3S,4R)-4-(4-chlorophenyl)-1-(3-pyridazin-4-yl-1H-...)
Copy SMILES
Affinity Data
IC50: 563nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776322
([(3R,4S)-3-(4-chlorophenyl)-4-hydroxy-pyrrolidin-1...)
Copy SMILES
Affinity Data
IC50: 624nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776336
([(3S)-3-(4-chlorophenyl)pyrrolidin-1-yl]-[3-(4-pyr...)
Copy SMILES
Affinity Data
IC50: 625nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776337
([(3R)-3-(6-chloro-3-pyridyl)pyrrolidin-1-yl]-[3-(4...)
Copy SMILES
Affinity Data
IC50: 682nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776344
([3-(4-chlorophenyl)pyrrolidin-1-yl]-(4-methoxy-3-p...)
Copy SMILES
Affinity Data
IC50: 698nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776349
(5-[1-(3-pyridazin-4-yl-1H-pyrazole-5-carbonyl)pyrr...)
Copy SMILES
Affinity Data
IC50: 746nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776378
([(3R)-3-(4-chloro-2-thienyl)pyrrolidin-1-yl]-(3-py...)
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Affinity Data
IC50: 749nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
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WIPO WO2025045746
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Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776340
([(3S,4R)-3-(4-chlorophenyl)-4-hydroxy-pyrrolidin-1...)
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Affinity Data
IC50: 761nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
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WIPO WO2025045746
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Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776345
([3-(4-chlorophenyl)pyrrolidin-1-yl]-[3-(3-fluoro-4...)
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Affinity Data
IC50: 1.22E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
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Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776370
([(3S,4R)-3-(4-chlorophenyl)-4-(hydroxymethyl)pyrro...)
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Affinity Data
IC50: 1.24E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
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Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776316
([3-(3-chlorophenyl)pyrrolidin-1-yl]-[3-(4-pyridyl)...)
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Affinity Data
IC50: 1.29E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
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Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776386
([(3R,4S)-3-(3,4-difluorophenyl)-4-(hydroxymethyl)p...)
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Affinity Data
IC50: 1.32E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
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Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776361
([(3R,4S)-3-(4-bromophenyl)-4-methyl-pyrrolidin-1-y...)
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Affinity Data
IC50: 1.36E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
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Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776354
([3-(5-methyl-2-thienyl)pyrrolidin-1-yl]-(3-pyridaz...)
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Affinity Data
IC50: 1.54E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
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Target
NAD(+) hydrolase SARM1 [28-724]
(Human)
695 Avenue de la Résistance
WIPO
Ligand
BDBM776368
((4-bromo-3-pyridazin-4-yl-1H-pyrazol-5-yl)-[(3S)3-...)
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Affinity Data
IC50: 1.78E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/24/2026
Entry Details
Copy BDB DOI
WIPO WO2025045746
Copy reaction URL
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