Compile Data Set for Download or QSAR
Report error Found 97 Enz. Inhib. hit(s) with all data for entry = 13382
TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784823(N-(4-chloro-3-(cis-3-hydroxycyclobutyl)phenyl)-3-m...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784822(N-(4-chloro-3-(trans-3-hydroxycyclobutyl)phenyl)-3...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784821(N-(4-chloro-3-((1S,2R)-2-cyanocyclobutyl)-5-fluoro...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784820(N-(4-chloro-3-((1R,2S)-2-cyanocyclobutyl)-5-fluoro...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784819(N-(4-chloro-3-((1S,2R)-2-cyanocyclobutyl)phenyl)-3...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784818(N-(4-chloro-3-((1R,2S)-2-cyanocyclobutyl)phenyl)-3...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784817(N-(3-(trans-2-(4H-1,2,4-triazol-4-yl)cyclobutyl)-4...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784816(N-(3-(cis-2-(2H-1,2,3-triazol-2-yl)cyclobutyl)-4-c...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784830(N-(4-chloro-3-(cis-2-cyanocyclobutyl)phenyl)-3-(tr...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784829(N-(4-chloro-3-(cis-3-hydroxycyclobutyl)phenyl)-3-(...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784828(N-(4-chloro-3-(trans-3-hydroxycyclobutyl)phenyl)-3...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784826(N-(4-chloro-3-((1R,2S)-2-(difluoromethyl)cyclobuty...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784825(N-(4-chloro-3-(3-hydroxy-3-methylcyclobutyl)phenyl...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784824(N-(4-chloro-3-(3-hydroxy-3-methylcyclobutyl)phenyl...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784806(N-(3-(bicyclo[1.1.1]pentan-1-yl)-4-chlorophenyl)-3...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784805(N-(4-chloro-3-(1-fluorocyclobutyl)phenyl)-3-methyl...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784804(N-(4-chloro-3-cyclobutylphenyl)-3-methyl-6-azabicy...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784803(N-(4-chloro-3-((1S,2R)-2-cyanocyclopropyl)phenyl)-...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784814(N-(3-(cis-2-(1H-1,2,3-triazol-1-yl)cyclobutyl)-4-c...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784813(N-(3-(trans-2-(1H-1,2,3-triazol-1-yl)cyclobutyl)-4...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784811(WO2025054369, Example 25)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784810(WO2025054369, Example 24)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784809(WO2025054369, Example 23)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784854((1S,3R,5R)-N-(4-chloro-3-cyclobutylphenyl)-1-(5-me...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784853(N-(4-chloro-3-((1S,3R)-3-hydroxy-3-methylcyclopent...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784852(N-(4-chloro-3-((1R,3S)-3-hydroxy-3-methylcyclopent...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784850(N-(4-chloro-3-((1S,3S)-3-hydroxy-3-methylcyclopent...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784849(N-(4-chloro-3-((1R,2R)-2-cyanocyclopentyl)phenyl)-...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784848(N-(4-chloro-3-((1S,2S)-2-cyanocyclopentyl)phenyl)-...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784863(WO2025054369, Example 77)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784862(WO2025054369, Example 76)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784861(WO2025054369, Example 75)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784860(WO2025054369, Example 74)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784858(N-(4-chloro-3-((S)-2-cyanoazetidin-1-yl)phenyl)-3-...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784857(N-(4-chloro-3-((R)-2-cyanoazetidin-1-yl)phenyl)-3-...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784856((1R,3S,5S)-N-(4-chloro-3-(3-hydroxyazetidin-1-yl)p...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784839(N-(3-((1S,2R)-2-cyanocyclobutyl)-4-(trifluoromethy...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784837(N-(4-chloro-3-((1R,2R)-2-(difluoromethyl)cyclobuty...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784836(N-(4-chloro-3-((1S,2S)-2-(difluoromethyl)cyclobuty...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784835(N-(4-chloro-3-(cis-3-fluorocyclobutyl)phenyl)-3-me...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784834(N-(4-chloro-3-(trans-3-fluorocyclobutyl)phenyl)-3-...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784832(N-(4-chloro-3-((1S,2S)-2-hydroxy-2-methylcyclobuty...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784847(N-(4-chloro-3-((1S,2R)-2-cyanocyclopentyl)phenyl)-...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784846(N-(4-chloro-3-((1R,2S)-2-cyanocyclopentyl)phenyl)-...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784843(N-(4-chloro-3-((1S,2R)-2-cyanocyclobutyl)phenyl)-3...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784841(N-(3-((1R,2R)-2-cyanocyclobutyl)-4-(trifluoromethy...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784840(N-(3-((1S,2S)-2-cyanocyclobutyl)-4-(trifluoromethy...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784882(WO2025054369, Example 96)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784881(WO2025054369, Example 95)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandPNGBDBM784870(WO2025054369, Example 84)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details WIPO WO2025054369

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