Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 4370
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65922BDBM65922(cid_886930 | 1-[(2,4-dichlorophenyl)methyl]-3-phen...)
Affinity DataEC50:  2.22E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65947BDBM65947(1-(6-chloro-3-pyridinyl)-3-(3-fluorophenyl)urea | ...)
Affinity DataEC50:  2.81E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65944BDBM65944(cid_45489561 | 1-(6-chloro-3-pyridinyl)-3-[(2,4-di...)
Affinity DataEC50:  3.74E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65949BDBM65949(1-(6-bromo-3-pyridinyl)-3-(3-fluorophenyl)urea | c...)
Affinity DataEC50:  4.04E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65931BDBM65931(VU0183535-1 | 1-(3-chloranyl-4-fluoranyl-phenyl)-3...)
Affinity DataEC50:  4.21E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65886BDBM65886(SMR000502476 | 1-(4-phenoxyphenyl)-3-pyridin-3-yl-...)
Affinity DataEC50:  4.45E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65946BDBM65946(1-(3-fluorophenyl)-3-(6-fluoropyridin-3-yl)urea | ...)
Affinity DataEC50:  5.76E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65923BDBM65923(MLS001201441 | 1-(3-fluorophenyl)-3-pyridin-3-ylur...)
Affinity DataEC50:  6.28E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65943BDBM65943(cid_45489560 | 1-[(2,4-dichlorophenyl)methyl]-3-(6...)
Affinity DataEC50:  6.31E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65951BDBM65951(1-(3-fluorophenyl)-3-(5-fluoro-3-pyridinyl)urea;2,...)
Affinity DataEC50:  6.32E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65948BDBM65948(1-(6-bromo-5-methyl-3-pyridinyl)-3-(3-fluorophenyl...)
Affinity DataEC50:  6.61E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65926BDBM65926(1-(4-chlorophenyl)-3-pyridin-3-yl-urea | VU0136203...)
Affinity DataEC50:  6.85E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65945BDBM65945(1-[(2,4-dichlorophenyl)methyl]-3-(5-fluoranylpyrid...)
Affinity DataEC50:  8.64E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65934BDBM65934(VU0414987-1 | 1-(3-fluoranyl-4-methyl-phenyl)-3-py...)
Affinity DataEC50:  9.14E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65935BDBM65935(1-(3-chlorophenyl)-3-(3-pyridinyl)thiourea | 1-(3-...)
Affinity DataEC50:  9.33E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65941BDBM65941(VU0415006-1 | 1-(3,5-dimethylphenyl)-3-pyridin-3-y...)
Affinity DataEC50:  1.07E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65933BDBM65933(1-(4-anilinophenyl)-3-(3-pyridinyl)thiourea | cid_...)
Affinity DataEC50:  1.10E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65950BDBM65950(VU0417943-1 | 1-(3-fluorophenyl)-3-(5-methylpyridi...)
Affinity DataEC50:  1.24E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65936BDBM65936(1-(4-butan-2-ylphenyl)-3-pyridin-3-yl-thiourea | 1...)
Affinity DataEC50:  1.26E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65940BDBM65940(1-(3,4-dimethylphenyl)-3-(3-pyridinyl)urea | cid_6...)
Affinity DataEC50:  1.35E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65938BDBM65938(VU0414998-1 | 1-(4-butylphenyl)-3-(3-pyridinyl)ure...)
Affinity DataEC50:  1.37E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65939BDBM65939(1-(4-ethoxyphenyl)-3-pyridin-3-yl-urea | cid_64665...)
Affinity DataEC50:  1.43E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65937BDBM65937(1-(2,3-dimethylphenyl)-3-pyridin-3-ylurea | cid_18...)
Affinity DataEC50:  1.60E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65942BDBM65942(1-(3-methylphenyl)-3-pyridin-3-yl-urea | 1-(3-meth...)
Affinity DataEC50:  1.68E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65928BDBM65928(1-(3-chlorophenyl)-3-pyridin-3-ylurea | 1-(3-chlor...)
Affinity DataEC50:  1.83E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65927BDBM65927(cid_674807 | 1-phenyl-3-pyridin-3-yl-urea | 1-phen...)
Affinity DataEC50:  2.18E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65929BDBM65929(VU0407296-1 | 1-(3-fluorophenyl)-3-pyridin-3-ylthi...)
Affinity DataEC50:  4.19E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65925BDBM65925(VU0414967-1 | 1-(4-methylphenyl)-3-(3-pyridinyl)ur...)
Affinity DataEC50:  1.28E+5nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65930BDBM65930(VU0155960-1 | 1-(1,3-benzodioxol-5-yl)-3-(3-pyridi...)
Affinity DataEC50:  1.52E+5nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65924BDBM65924(cid_2837290 | 1-(4-methoxyphenyl)-3-pyridin-3-yl-u...)
Affinity DataEC50:  2.03E+5nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65932BDBM65932(1-(4-butylphenyl)-3-pyridin-3-ylthiourea | 1-(4-bu...)
Affinity DataEC50:  2.68E+5nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay