Solution Informationhelp
Enzyme: Beta-lactamase
inhibitor: BDBM51078
substrate: n/a
 
Solution Type: Aqueous
pH at Preparation: n/a
Temp. Prep.: n/a
Comments: Assay Overview: The purpose of this assay is to determine dose response curves for common IMP-1/VIM-2 inhibitor compounds identified as active in a previous set of experiments entitled, "Primary biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase" (PubChem AID 1556), and "Primary biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase" (PubChem AID 1527), and that confirmed activity in a set of experiments entitled, "Epi-absorbance-based confirmation assay for common VIM-2 and IMP-1 inhibitors: biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase " (AID 2187), and "Epi-absorbance-based confirmation assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase" (AID 2189). Compounds selected for testing also were inactive in a set of previous experiments entitled, "Epi-a
 
 

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