Solution Information | help | |
Enzyme: | Beta-lactamase | |
inhibitor: | BDBM66150 | |
substrate: | n/a | |
Solution Type: | Aqueous | |
pH at Preparation: | n/a | |
Temp. Prep.: | n/a | |
Comments: | Assay Overview: The purpose of this counterscreen is to determine dose response curves for common IMP-1/VIM-2 inhibitor compounds identified as active in a previous set of experiments entitled, "Primary biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase" (PubChem AID 1556), and "Primary biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase" (PubChem AID 1527), and that confirmed activity in a set of experiments entitled, "Epi-absorbance-based confirmation assay for common VIM-2 and IMP-1 inhibitors: biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase " (AID 2187), and "Epi-absorbance-based confirmation assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase" (AID 2189). Compounds selected for testing also were inactive in a set of previous experiments entitled | |
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