Reaction Details  Report a problem with these data
Cell Reactant:
Transthyretin
Syringe Reactant:
BDBM138363
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
08/28/22
ΔG°:
-9.19±0.48 (kcal/mole)
pH:
7.5±0
Temperature:
298.15±0 (K)
ΔH° :
-13.52±0.31 (kJ/mole)
ΔS° :
-0.01±0 (kJ/mole-K)
Citation
 Graef, IA; Alhamadsheh, MM Identification of stabilizers of multimeric proteins US Patent  US11337935 Publication Date 5/24/2022 
Cell React
Name:
Transthyretin
Synonyms:
ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:
Enzyme
Mol. Mass.:
15884.31
Organism:
Human
Description:
P02766
Residue:
147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
  
Syringe React
Name:
BDBM138363
Synonyms:
US10278929, Compound Ro-41-0960 | US11337935, Compound Ro-41-0960 | US8877795, Ro 41-0960
Type:
Small organic molecule
Emp. Form.:
C13H8FNO5
Mol. Mass.:
277.2047
SMILES:
Oc1cc(cc(c1O)[N+]([O-])=O)C(=O)c1ccccc1F
Structure:
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